ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7)
- CAS No.
- Chemical Name:
- ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7)
- Synonyms
- Anti-SIR2L;Anti-SIR2L7;Anti-SIR2L2;Anti-MGC126842;Anti-MGC126840;Anti-sirtuin 2;Anti-Sirtuin 7;Anti-Sir2-related protein type 7;ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7);Anti-SIRT7 antibody produced in chicken
- CBNumber:
- CB7489330
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD07784768
- MOL File:
- Mol file
ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7) price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | WH0022933M1 | Monoclonal Anti-SIRT2 antibody produced in mouse clone 4B11, purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB3500498 | Anti-SIRT7 antibody produced in chicken affinity isolated antibody, buffered aqueous solution | 100μG | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | S5947 | Anti-Sirt7 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 200μL | $503 | 2023-06-20 | Buy | |
| Sigma-Aldrich | AV32406 | Anti-SIRT7 antibody produced in rabbit affinity isolated antibody | 100μL | $434 | 2023-01-07 | Buy | |
| Sigma-Aldrich | AV32385 | Anti-SIRT2 (AB2) antibody produced in rabbit affinity isolated antibody | 100μL | $503 | 2023-01-07 | Buy |
ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7) Chemical Properties,Uses,Production
Uses
Anti-Sirt7 antibody produced in rabbit has been used in western blotting analysis and immunofluorescence detection.
General Description
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. (provided by RefSeq)
Biochem/physiol Actions
Sirt7 (sirtuin 7) is extensively found in protein associated with active rRNA genes (rDNA), in the nucleolus. It interacts with RNA polymerase I (Pol I) and histones. Overexpression of Sirt7 increases Pol I-mediated transcription, whereas knockdown of Sirt7 or inhibition of its catalytic activity results in decreased association of Pol I with rDNA and reduces Pol I transcription. Depletion of Sirt7 stops cell proliferation and triggers apoptosis. High levels of Sirt7 expression are associated with breast cancer.
ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN SIRTUIN TYPE 7 (SIRT 7) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |