ChemicalBook >> CAS DataBase List >>1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone
1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone
- CAS No.
- 50405-58-8
- Chemical Name:
- 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone
- Synonyms
- TC-E 5008;TC E 5008,TCE 5008;6-benzyl-1-hydroxy-4-methylpyridin-2(1H)-one;1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone;2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(phenylmethyl)-
- CBNumber:
- CB74902655
- Molecular Formula:
- C13H13NO2
- Molecular Weight:
- 215.25
- MDL Number:
- MFCD30290154
- MOL File:
- 50405-58-8.mol
Last updated:2023-07-22 08:27:57
1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 5244 | TC-E5008 | 50405-58-8 | 10 | $152 | 2021-12-16 | Buy |
Tocris | 5244 | TC-E5008 | 50405-58-8 | 50 | $642 | 2021-12-16 | Buy |
TRC | T125135 | TC-E5008 | 50405-58-8 | 10mg | $145 | 2021-12-16 | Buy |
TRC | T125135 | TC-E5008 | 50405-58-8 | 50mg | $630 | 2021-12-16 | Buy |
1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Chemical Properties,Uses,Production
Uses
TC-E 5008 is a cancer-assocaited mutant isocitrate dehydrogenase inhibitor, which was found to be permeable through the blood-brain barrier.
Definition
ChEBI: SYC-435 is a cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and benzyl groups, respectively. It is a potent inhibitor of mutant isocitrate dehydrogenase 1 (Ki values of 190 nM against R132H mutant and 120 nM against R132C mutant). It has a role as an EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor and an antineoplastic agent. It is a member of benzenes, a pyridone and a cyclic hydroxamic acid.
Synthesis of 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone from 2H-Pyran-2-one, 4-methyl-6-(phenylmethyl)-
1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Preparation Products And Raw materials
Raw materials
Preparation Products
1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Suppliers
Global( 13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3770 | 55 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4565 | 58 |
1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone
TC-E 5008
2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(phenylmethyl)-
6-benzyl-1-hydroxy-4-methylpyridin-2(1H)-one
TC E 5008,TCE 5008
50405-58-8