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VU6005806

VU6005806 structure

CAS No.: 2180914-37-6

Chemical Name:: VU6005806

Synonyms: VU6005806;AZN-00016130;VU6005806,VU-6005806;Thieno[2,3-c]pyridazine-6-carboxamide, 5-amino-3-methoxy-4-methyl-N-[1-[5-(trifluoromethyl)-2-pyrimidinyl]-3-azetidinyl]-

CBNumber:: CB75821342

Molecular Formula:: C17H16F3N7O2S

Molecular Weight:: 439.41

MDL Number:: MFCD32067965

MOL File:: 2180914-37-6.mol

Last updated:2023-05-21 10:59:17

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VU6005806 Properties

Density	1.59±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	11.44±0.20(Predicted)

VU6005806 Chemical Properties,Uses,Production

Description

VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders[1]. IC50: 94 nM (Human M4), 28 nM (Rat M4), 87 nM (Dog M4), 68 nM (Cyno M4)[1]

References

[1]. Engers DW, et al. VU6005806/AZN-00016130, an advanced M4 positive allosteric modulator (PAM) profiled as a potential preclinical development candidate. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1714-1718.

VU6005806 Preparation Products And Raw materials

Raw materials

Preparation Products

VU6005806 Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58

2180914-37-6(VU6005806)Related Search:

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VU6005806 AZN-00016130 VU6005806,VU-6005806 Thieno[2,3-c]pyridazine-6-carboxamide, 5-amino-3-methoxy-4-methyl-N-[1-[5-(trifluoromethyl)-2-pyrimidinyl]-3-azetidinyl]- 2180914-37-6