ChemicalBook >> CAS DataBase List >>LDN-0088050
LDN-0088050
- CAS No.
- 353484-30-7
- Chemical Name:
- LDN-0088050
- Synonyms
- LDN-0088050;LDN0088050,LDN 0088050;Benzo[ij]dicyclopenta[b,g]quinolizine-7-carboxylic acid, 2-bromo-3b,6,6a,7,9,9a,10,12a-octahydro-
- CBNumber:
- CB75821443
- Molecular Formula:
- C19H18BrNO2
- Molecular Weight:
- 372.26
- MDL Number:
- MFCD01081201
- MOL File:
- 353484-30-7.mol
Last updated:2023-05-21 10:59:17
LDN-0088050 Chemical Properties,Uses,Production
Description
LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM[1]. Ki: 0.29 μM (FABP4), 1.3 μM (FABP3)[1]Kd: 2.05 μM (FABP4)[1]
LDN 0088050 significantly inhibits LPS-induced expression of both TNFα and IL-6 in RAW264.7 cells[1].
References
[1]. Zhou Y, et al. The discovery of novel and selective fatty acid binding protein 4 inhibitors by virtual screening and biological evaluation. Bioorg Med Chem. 2016 Sep 15;24(18):4310-4317.
LDN-0088050 Preparation Products And Raw materials
Raw materials
Preparation Products
LDN-0088050 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7980 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 58 |
LDN-0088050
LDN0088050,LDN 0088050
Benzo[ij]dicyclopenta[b,g]quinolizine-7-carboxylic acid, 2-bromo-3b,6,6a,7,9,9a,10,12a-octahydro-
353484-30-7