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LDN-0088050

LDN-0088050 Structure
LDN-0088050 structure
CAS No.
353484-30-7
Chemical Name:
LDN-0088050
Synonyms
LDN-0088050;LDN0088050,LDN 0088050;Benzo[ij]dicyclopenta[b,g]quinolizine-7-carboxylic acid, 2-bromo-3b,6,6a,7,9,9a,10,12a-octahydro-
CBNumber:
CB75821443
Molecular Formula:
C19H18BrNO2
Molecular Weight:
372.26
MDL Number:
MFCD01081201
MOL File:
353484-30-7.mol
Last updated:2024-10-23 13:36:13
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LDN-0088050 Properties

Boiling point 494.4±45.0 °C(Predicted)
Density 1.61±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 6.61±0.20(Predicted)

LDN-0088050 Chemical Properties,Uses,Production

Description

LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM[1]. Ki: 0.29 μM (FABP4), 1.3 μM (FABP3)[1]Kd: 2.05 μM (FABP4)[1]

LDN 0088050 significantly inhibits LPS-induced expression of both TNFα and IL-6 in RAW264.7 cells[1].

References

[1]. Zhou Y, et al. The discovery of novel and selective fatty acid binding protein 4 inhibitors by virtual screening and biological evaluation. Bioorg Med Chem. 2016 Sep 15;24(18):4310-4317.

LDN-0088050 Preparation Products And Raw materials

Raw materials

Preparation Products

LDN-0088050 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7979 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19707 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from LDN-0088050 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LDN-0088050 pictures 2024-10-24 LDN-0088050
353484-30-7
 US $1980.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • LDN-0088050 pictures
  • LDN-0088050
    353484-30-7
  • US $1980.00-1520.00 / mg
  • TargetMol Chemicals Inc.
LDN-0088050 LDN0088050,LDN 0088050 Benzo[ij]dicyclopenta[b,g]quinolizine-7-carboxylic acid, 2-bromo-3b,6,6a,7,9,9a,10,12a-octahydro- 353484-30-7