ORIENTIN
- CAS No.
- 28608-75-5
- Chemical Name:
- ORIENTIN
- Synonyms
- LUTEOLIN-8-C-GLUCOSIDE;Polygonin;Luteolin 8-C-β-D-glucopyranoside;lutexin;ORIENTIN;ORIENTINE;Aids026706;Aids-026706;ORIENTIN(P);ORIENTIN,NA
- CBNumber:
- CB7710333
- Molecular Formula:
- C21H20O11
- Molecular Weight:
- 448.38
- MDL Number:
- MFCD00017432
- MOL File:
- 28608-75-5.mol
Melting point | 260-285°C |
---|---|
Boiling point | 816.1±65.0 °C(Predicted) |
Density | 1.759±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C(protect from light) |
solubility | 1 M NaOH: soluble1mg/mL, clear, yellow-orange |
pka | 6.24±0.40(Predicted) |
form | powder |
color | yellow |
Stability | Hygroscopic |
LogP | 1.580 (est) |
FDA UNII | IAX93XCW6C |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DJ3009300 | |||||||||
HS Code | 29389090 | |||||||||
NFPA 704 |
|
ORIENTIN price More Price(37)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | O9765 | Orientin ≥97% (HPLC) | 28608-75-5 | 1mg | $134 | 2024-03-01 | Buy |
Sigma-Aldrich | 03810585 | Orientin primary pharmaceutical reference standard | 28608-75-5 | 10mg | $677 | 2024-03-01 | Buy |
Cayman Chemical | 25143 | Orientin ≥95% | 28608-75-5 | 25mg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 25143 | Orientin ≥95% | 28608-75-5 | 50mg | $95 | 2024-03-01 | Buy |
Sigma-Aldrich | O9765 | Orientin ≥97% (HPLC) | 28608-75-5 | 5mg | $496 | 2024-03-01 | Buy |
ORIENTIN Chemical Properties,Uses,Production
Description
Orientin is a flavone glycoside originally isolated from P. orientale that has diverse biological activities, including antioxidant, antibacterial, and anti-inflammatory properties. Orientin scavenges 2,2-diphenyl-1-picryl-hydrazyl (DPPH; ) radicals with an IC50 value of 316.21 μg/ml. It also decreases the cytopathic effects of parainfluenza type 3 virus with an IC50 value of 11.7 μg/ml and a cytotoxic concentration (CC50) value of 375 μg/ml in Hep-2 cells. Orientin (5-40 μM) inhibits LPS-induced barrier disruption, decreases the expression of toll-like receptor 4 (TLR4), phosphorylated p38, and NF-κB, and decreases TNF-α production and IL-6 secretion in a dose-dependent manner in human umbilical vein endothelial cells (HUVECs). It also prolongs survival in a mouse model of LPS-induced lethal endotoxemia when administered at a dose of 36 μg/animal 12 hours after LPS administration.
Chemical Properties
Yellow powder
Uses
Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
Definition
ChEBI: A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
ORIENTIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3777 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from ORIENTIN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2023-02-24 | Orientin
28608-75-5
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2023-02-13 | Orientin
28608-75-5
|
US $90.00 / kg | 1kg | 99% | 80MT | Hebei baicao biology science and technology co., ltd | |
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2021-07-13 | Orientine
28608-75-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
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