trans-Chalcone
- CAS No.
- 614-47-1
- Chemical Name:
- trans-Chalcone
- Synonyms
- (E)-CHALCONE;BENZALACETOPHENONE;cone;BENZYLIDENEACETOPHENONE;1,3-DIPHENYL-2-PROPEN-1-ONE;CHALKONE;1,3-DIPHENYL-2-PROPENONE;2-Propen-1-one, 1,3-diphenyl-, (E)-;Nsc167107;trans-ChaL
- CBNumber:
- CB7746253
- Molecular Formula:
- C15H12O
- Molecular Weight:
- 208.26
- MDL Number:
- MFCD00003082
- MOL File:
- 614-47-1.mol
- MSDS File:
- SDS
| Melting point | 55-59 °C |
|---|---|
| Boiling point | 208 °C25 mm Hg(lit.) |
| Density | 1.0712 |
| refractive index | 1.5361 (estimate) |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Solid |
| color | Pale Yellow |
| Odor | at 100.00 %. floral balsam herbal |
| Odor Type | floral |
| Water Solubility | Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water. |
| Merck | 14,2037 |
| BRN | 509985 |
| LogP | 4.013 (est) |
| CAS DataBase Reference | 614-47-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 5S5A2Q39HX |
| NIST Chemistry Reference | Benzalacetophenone(614-47-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P301+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37 | |||||||||
| Safety Statements | 22-36/37/39-45 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UD5576750 | |||||||||
| HS Code | 29143990 | |||||||||
| NFPA 704 |
|
trans-Chalcone price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 136123 | trans-Chalcone 97% | 614-47-1 | 5g | $42.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 136123 | trans-Chalcone 97% | 614-47-1 | 100g | $62.4 | 2024-03-01 | Buy |
| Alfa Aesar | A14734 | trans-Chalcone, 97% | 614-47-1 | 100g | $53 | 2024-03-01 | Buy |
| Alfa Aesar | A14734 | trans-Chalcone, 97% | 614-47-1 | 500g | $175 | 2024-03-01 | Buy |
| TRC | C291860 | trans-Chalcone | 614-47-1 | 5g | $65 | 2021-12-16 | Buy |
trans-Chalcone Chemical Properties,Uses,Production
Description
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Chemical Properties
Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.
Uses
trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.
Definition
ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.
Preparation
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones
Application
trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).
Synthesis Reference(s)
Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058
General Description
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Biological Activity
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Biochem/physiol Actions
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Synthesis
Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.
trans-Chalcone Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15354 | 58 |
| Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 | |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | sales06@tgybio.com | China | 902 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
View Lastest Price from trans-Chalcone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | trans-Chalcone
614-47-1
|
US $30.00 / g | 99.81% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-06-18 | trans-Chalcone
614-47-1
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Kingfiner Technology Development Co.Ltd | |
 |
2020-01-03 | trans-Chalcone
614-47-1
|
US $1.00 / KG | 1KG | 99% | 1000kgs | Career Henan Chemical Co |
-
- trans-Chalcone
614-47-1
- US $30.00 / g
- 99.81%
- TargetMol Chemicals Inc.
-
- trans-Chalcone
614-47-1
- US $0.00-0.00 / kg
- 0.99
- Hebei Kingfiner Technology Development Co.Ltd
-
- trans-Chalcone
614-47-1
- US $1.00 / KG
- 99%
- Career Henan Chemical Co