trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
화학적 성질
Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.
용도
trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.
주요 응용
trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).
제조 방법
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst. Clay-catalysed solventless synthesis of trans-chalcones
일반 설명
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
생물학적 활성
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Synthesis
Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.
