크리신
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크리신 속성
- 녹는점
- 284-286 °C(lit.)
- 끓는 점
- 357.45°C (rough estimate)
- 밀도
- 1.2693 (rough estimate)
- 굴절률
- 1.4872 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 6.50±0.40(Predicted)
- 물리적 상태
- 결정성 분말
- 색상
- 노란색
- Merck
- 14,2256
- BRN
- 233276
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- RTIXKCRFFJGDFG-UHFFFAOYSA-N
- LogP
- 3.520
- CAS 데이터베이스
- 480-40-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 22-24/25-36-26 | ||
WGK 독일 | 3 | ||
RTECS 번호 | LK8329050 | ||
F 고인화성물질 | 10 | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29329990 |
크리신 C화학적 특성, 용도, 생산
개요
Chrysin is a natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties. It blocks COX-2 gene expression, PGE2 production, and hydroxyl radical formation in LPS-induced RAW 264.7 cells. Chrysin inhibits insulin-induced HIF-1α expression (~50% at 10 μM) in human prostate cancer DU145 cells and blocks DU145 xenograft-induced angiogenesis in vivo. In a mouse model of ischemia/reperfusion injury, chrysin decreased pro-inflammatory gene expression and oxidative stress, resulting in a reduction of infarct volume and neurological defects.화학적 성질
beige powder or Pale yellow prismatic crystal (crystallized from methanol) with a melting point of 285°C. This substance is soluble in alkali hydroxide solution and acetone, slightly soluble in ether, ethanol and chloroform, insoluble in water.정의
ChEBI: Chrysin is a dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. It has a role as an anti-inflammatory agent, an antineoplastic agent, an antioxidant, a hepatoprotective agent, an EC 2.7.11.18 (myosin-light-chain kinase) inhibitor and a plant metabolite. It is a dihydroxyflavone and a 7-hydroxyflavonol.Source
The main sources of chrysin are honey and propolis, of which the content of chrysin in honey is 5.3 mg/kg and that in propolis is 28 g/L. In addition, chrysin is also found in various vegetables, fruits, herbs, and even mushrooms. Another source of populin is an endophytic fungus Chaetomium globosum, which is related to Chaetomorpha media from India. In addition, chrysin exists in the form of glycosides in walnut, walnut skin, walnut flower and pericarp passion fruit, and in the form of 6-c-arabinoside-8-c-glucoside or glucuronic acid ester in Pinellia ternata.크리신 준비 용품 및 원자재
원자재
준비 용품
크리신 공급 업체
글로벌( 612)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
PNP Biotech Co. Ltd | +8618516098983 |
sales@pnpbiotech.com | China | 1001 | 58 |
Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 |
sales006@ingredients-lonier.com | China | 2605 | 58 |
Shaanxi Dideu Medichem Co. Ltd | 18192627656 |
1012@dideu.com | China | 3002 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12495 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 2990 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 |
clara@hbshengyang.com | China | 874 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |