다이하이드록시아세톤
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다이하이드록시아세톤 속성
- 녹는점
- 75-80 °C
- 끓는 점
- 107.25°C (rough estimate)
- 밀도
- 1.1385 (rough estimate)
- 증기압
- 0.002-0.33Pa at 20-50℃
- 굴절률
- 1.4540 (estimate)
- 저장 조건
- Store at +2°C to +8°C.
- 용해도
- >112.4 mg/mL in DMSO; >5.09 mg/mL in EtOH with ultrasonic
- 산도 계수 (pKa)
- 12.45±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 하얀색
- 냄새
- 100.00%에서. 민트티
- ?? ??
- 민트 맛
- 수용성
- >250g/L(20℃)
- JECFA Number
- 1716
- 안정성
- 안정적인. 타기 쉬운. 흡습성.
- LogP
- -1.95 at 20℃
- 표면장력
- 68.85mN/m at 1g/L and 20℃
- CAS 데이터베이스
- 96-26-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
안전지침서 | 24/25 | ||
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HS 번호 | 29141900 | ||
유해 물질 데이터 | 96-26-4(Hazardous Substances Data) | ||
독성 | CHROMELIN ? DIHYDROXYACETONE ? 1,3DIHYDROXYACETONE ? 1,3-DIHYDROXYPROPANONE ? DIHYXAL ? NSC-24343 ? OTAN ? OXATONE ? SOLEAL ? 2PROPANONE, 1,3-DIHYDROXY- ? TRIULOSE ? VITICOLOR | ||
기존화학 물질 | KE-10860 |
그림문자(GHS): | |||||||||||||||||||||||||||||
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신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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다이하이드록시아세톤 C화학적 특성, 용도, 생산
개요
다이하이드록시아세톤은 3개의 탄소 원자가 포함된 단당류이고, 케톤기를 가지고 있는 케토스이며, 화학식은 C3H6O3이다.용도
다이하이드록시아세톤의 인산화된 형태인 다이하이드록시아세톤 인산은 해당과정의 중간생성물이며, 과당 대사의 중간생성물이다.화학적 성질
white powder출처
A derivative of naturally occurring starch용도
1,3-Dihydroxyacetone can be used as artificial tanning agent.정의
ChEBI: Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a ketotriose and a primary alpha-hydroxy ketone.제조 방법
1,3-dihydroxyacetone (DHA) is prepared by acetalization, oxidation, and hydrolysis of glycerol. Usually produced commercially from Bacillus macerans or Bacillus circulans fermentation of starch or starch hydrolysate일반 설명
Dihydroxyacetone (DHA) is a browning ingredient widely used in cosmetics such as sunless tanning formulations. It participates in a chemical staining reaction called Milliard reaction in which it reacts with the amino groups of proteins to result in a mixture of high molecular weight pigments.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Safety Profile
Mutation data reported. When heated to decompositionit emits acrid smoke and irritating vapors.Safety
Cells that were treated with 1,3-Dihydroxyacetone (DHA) showed dose- and time-dependent changes that included cytoplasmic budding, chromatin condensation, and cell detachment. There was a significant decrease in cell proliferation after 24 hours of DHA exposure. After exposure to a 5% DHA solution for 21 days, epidermal thickening and dermatitis of the skin were noted in laboratory animals. After 42 days of treatment with the same solution, hyperplastic and dyskeratotic changes and moderate inflammatory reactions were seen. Long-lasting topical tanning products contain the sugars DHA or erythrulose, which cause a "Maillard reaction" when contacting proteins in the outer layers of the stratum corneum and epidermis. This reaction happens when free amino acids from skin proteins combine with DHA in the stratum corneum. This combination creates the tanned appearance of skin. Results are generally seen within a few hours of application. UV light exposure is not needed to initiate this chemical reaction[1].다이하이드록시아세톤 준비 용품 및 원자재
원자재
준비 용품
다이하이드록시아세톤 공급 업체
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