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2,5-Dichloropyrimidine

CAS No.
22536-67-0
Chemical Name:
2,5-Dichloropyrimidine
Synonyms
EOS-60492;2,5-Dichlo;2,5-chloropyrimidine;2,5-DICHLOROPYRIMIDINE;Macitentan Impurity 32;2,5‐Dichloropyridimidine;2,5-Dichloro-1,3-diazine;Pyrimidine, 2,5-dichloro-;2,5-Dichloropyrimidine>2,5-Dichloropyrimidine 97%
CBNumber:
CB7750461
Molecular Formula:
C4H2Cl2N2
Molecular Weight:
148.98
MDL Number:
MFCD00673131
MOL File:
22536-67-0.mol
MSDS File:
SDS
Last updated:2024-07-26 17:49:17

2,5-Dichloropyrimidine Properties

Melting point 48-55 °C
Boiling point 190°C
Density 1.493
Flash point 140°C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -2.84±0.22(Predicted)
form Powder
color Off-white
Water Solubility Slightly soluble in water.
λmax 268nm(EtOH)(lit.)
InChI InChI=1S/C4H2Cl2N2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey CEJAHXLRNZJPQH-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(Cl)C=N1
CAS DataBase Reference 22536-67-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H318-H400
Precautionary statements  P273-P280-P301+P312+P330-P305+P351+P338+P310
Hazard Codes  C,N,Xn
Risk Statements  22-41-50
Safety Statements  26-39-61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
HazardClass  LACHRYMATOR, CORROSIVE
HazardClass  9
PackingGroup 
HS Code  29335990
NFPA 704
1
2 0

2,5-Dichloropyrimidine price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 720917 2,5-Dichloropyrimidine 97% 22536-67-0 1g $10.4 2024-03-01 Buy
TCI Chemical D4045 2,5-Dichloropyrimidine >98.0%(GC) 22536-67-0 5g $37 2024-03-01 Buy
TCI Chemical D4045 2,5-Dichloropyrimidine >98.0%(GC) 22536-67-0 25g $148 2024-03-01 Buy
Alfa Aesar H64066 2,5-Dichloropyrimidine, 95% 22536-67-0 5g $32.65 2024-03-01 Buy
Alfa Aesar H64066 2,5-Dichloropyrimidine, 95% 22536-67-0 25g $127.65 2024-03-01 Buy
Product number Packaging Price Buy
720917 1g $10.4 Buy
D4045 5g $37 Buy
D4045 25g $148 Buy
H64066 5g $32.65 Buy
H64066 25g $127.65 Buy

2,5-Dichloropyrimidine Chemical Properties,Uses,Production

Uses

2,5-Dichloropyrimidine acid is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Preparation

2,5-Dichloropyrimidine was synthesised from 2-hydroxypyrimidine hydrochloride by treatment with aqueous chlorine solution. Reaction of the product with phosphoryl chloride in the presence of N,N-dimethylaniline gave the desired product in 40% yield. The sample was then purified by sublimation.

storage

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

structure and hydrogen bonding

C4H2Cl2N2, M=148.98 monoclinic, space group P21/m with a=6.077(3), b=19.771(8), c=7.399(3) ?, β=101.23(6)°, U=872 ?3 [from 2θ values of 29 reflections measured at±ω, 25 ≤2θ ≤ 38°, λ = 0.710 73?, T=150.0 K], Dcalc=1.702 g cm-3, Z=6, μ =0.993 mm-1[1].

References

[1] Blake A, et al. Structure Analysis Restrained by ab Initio Calculations: The Molecular Structure of 2,5-Dichloropyrimidine in Gaseous and Crystalline Phases. The Journal of Physical Chemistry, 1996; 100: 12280–12287.

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View Lastest Price from 2,5-Dichloropyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dichloropyrimidine pictures 2024-10-11 2,5-Dichloropyrimidine
22536-67-0
US $9.00 / KG 1KG 99.9 1 ton Hebei Chuanghai Biotechnology Co,.LTD
2,5-Dichloropyrimidine pictures 2024-04-27 2,5-Dichloropyrimidine
22536-67-0
US $1250.00 / Kg 1Kg 98 500 Kg R&D Scientific Inc.
2,5-Dichloropyrimidine pictures 2024-04-08 2,5-Dichloropyrimidine
22536-67-0
US $36.00-1.10 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

2,5-Dichloropyrimidine Spectrum

2,5-DICHLOROPYRIMIDINE Pyrimidine, 2,5-dichloro- (7CI,8CI,9CI) 2,5-DICHLOROPYRIMIDINE,PURITY:95% MIN(HPLC) Pyrimidine, 2,5-dichloro- 2,5-chloropyrimidine 2,5-DichloropyriMidine 97+% 2,5-Dichloro-1,3-diazine 2,5-DichloropyriMidine 97+%, 5-DichloropyriMidine 97+% 2,5-Dichloropyrimidine 97% EOS-60492 2,5‐Dichloropyridimidine 2,5-Dichlo 2,5-DICHLOROPYRIMIDINE,PURITY Macitentan Impurity 32 2,5-Dichloropyrimidine> 22536-67-0 84-73-3 22536-60-0 Heterocycle-Pyrimidine series Building Blocks C4 to C5 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines Chlorinated heterocyclic series PYRIMIDINE Pyrimidine Series Pyridines, Pyrimidines, Purines and Pteredines