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2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-

2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- structure

CAS No.: 1638957-17-1

Chemical Name:: 2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-

Synonyms: ML395;ML-395;ML 395;VU0468809;VU-0468809;VU 0468809;2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-

CBNumber:: CB78556399

Molecular Formula:: C26H29N5O2

Molecular Weight:: 443.54

MDL Number:: MFCD28502199

MOL File:: 1638957-17-1.mol

Last updated:2023-03-31 09:12:59

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2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- Properties

Boiling point	757.5±60.0 °C(Predicted)
Density	1.30±0.1 g/cm3(Predicted)
pka	14.55±0.46(Predicted)

2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- Chemical Properties,Uses,Production

Description

ML395, also known as VU0468809, is a potent PLD2 inhibitor. ML39 showed potent antiviral activity. ML395 (VU0468809), a potent, >80-fold PLD2 selective allosteric inhibitor (cellular PLD1, IC50 >30,000 nM; cellular PLD2, IC50 =360 nM). Moreover, ML395 possesses an attractive in vitro DMPK profile, improved physiochemical properties, ancillary pharmacology (Eurofins Panel) cleaner than any other reported PLD inhibitor, and has been found to possess interesting activity as an antiviral agent in cellular assays against a range of influenza strains (H1, H3, H5 and H7).

2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

2-Naphthalenecarboxamide, N-[2-[4-oxo-1-(3-pyridinylmethyl)-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- ML 395 ML395 ML-395 VU 0468809 VU0468809 VU-0468809 1638957-17-1