TETANUS TOXIN
- CAS No.
- 676570-37-9
- Chemical Name:
- TETANUS TOXIN
- Synonyms
- tetanus toxin from clostridium tetani
- CBNumber:
- CB7972641
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01095768
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H300+H330-H311 |
Precautionary statements | P260-P264-P270-P280-P302+P352+P312-P304+P340+P310 |
Hazard Codes | T+ |
Risk Statements | 26/27/28 |
Safety Statements | 28-36/37/39-45-36/37 |
RIDADR | UN 3462 6.1/PG 1 |
WGK Germany | 3 |
TETANUS TOXIN price More Price(2)
TETANUS TOXIN Chemical Properties,Uses,Production
Uses
Tetanus toxin is the tetanus toxin produced by the anaerobic bacillus?Clostridium tetani.
Uses
Tetanus toxin from Clostridium tetani has been used as the exocytosis inhibitor/Golgi-dependent secretion to examine whether secretory carrier membrane protein (SCAMP5) stimulated α-synuclein secretion via the conventional Golgi-dependent pathway. It has also been used in peripheral blood mononuclear cells (PBMCs) culture for?T?cell?proliferation screening.
General Description
Tetanus toxin is also known as tetanospasmin. It is a 150-kDa protein, produced by Clostridium tetani. This protein consists of a light and a heavy chain.
Biochem/physiol Actions
Binds to polysialogangliosides acceptors on surface of all peripheral presynaptic nerve terminals. Internalized by receptor-mediated endocytosis and carried to spinal cord and brain by transsynaptic retrograde transport. Blocks the release of glycine from inhibitory interneurons of the spinal cord. Cleaves synaptobrevin (VAMP-2), and blocks synaptic vesicle exocytosis in vivo.
TETANUS TOXIN Preparation Products And Raw materials
Raw materials
Preparation Products
TETANUS TOXIN Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17987 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 58 |
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