ChemicalBook >> CAS DataBase List >>INDEX NAME NOT YET ASSIGNED
INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2490668-30-7
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- BAMEA-O16B;bis(2-(dodecyldisulfanyl)ethyl) 3,3'-((3-methyl-9-oxo-10-oxa-13,14-dithia-3,6-diazahexacosyl)azanediyl)dipropanoate
- CBNumber:
- CB79778387
- Molecular Formula:
- C56H111N3O6S6
- Molecular Weight:
- 1114.88
- MDL Number:
- MOL File:
- 2490668-30-7.mol
Last updated:2024-07-30 14:17:11
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H302-H319-H336 | |||||||||
Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P330-P303+P361+P353-P304+P340-P305+P351+P338-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
NFPA 704 |
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INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Description
BAMEA-O16B is a disulfide bond-containing ionizable cationic lipid.1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in vitro and in vivo. LNPs containing BAMEA-O16B encapsulating Cas9 mRNA and sgRNAs targeting the gene encoding proprotein convertase subtilisin kexin type 9 (PCSK9) accumulate in the liver and decrease serum PCSK9 levels in mice.
References
1. Liu, J., Chang, J., Jiang, Y., et al. Fast and efficient CRISPR/Cas9 genome editing in vivo enabled by bioreducible lipid and messenger RNA nanoparticles Adv. Mater. 31(33),e1902575(2019).
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
Global( 13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | changaiwei@sinopeg.com | China | 183 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10977 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
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Shanghai Changyu Medical Technology Co. Ltd. | +86-13301875428 | sales@changyuhe.com | China | 298 | 58 |
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DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
Shanghai Easy CDMO Co.,Ltd | 021-61734564 | August@easycdmo.com | China | 10010 | 58 |
Shandong Mopai Biotechnology Co., Ltd | 13053322091 13053322091 | admin@mopaikeji.com | China | 11056 | 58 |
View Lastest Price from INDEX NAME NOT YET ASSIGNED manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-07-30 | BAMEA-O16B
2490668-30-7
|
US $0.00-0.00 / g | 1g | 98% | 1g/bottle , 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. |
- BAMEA-O16B
2490668-30-7
- US $0.00-0.00 / g
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
BAMEA-O16B
bis(2-(dodecyldisulfanyl)ethyl) 3,3'-((3-methyl-9-oxo-10-oxa-13,14-dithia-3,6-diazahexacosyl)azanediyl)dipropanoate
2490668-30-7
C56H111N3O6S6