Cryptochlorogenic acid
- CAS No.
- 905-99-7
- Chemical Name:
- Cryptochlorogenic acid
- Synonyms
- 4-Caffeoylquinic acid;4-Dicaffeoylquinic Acid;Cryptochlorogenin Acid;Cryptochlorogenic acid;Quinic acid 4-O-caffeate;Cryptochlorogenic acid-RM;Cryptochlorogenic acid(4');4-O-trans-caffeoylquinicaci;4-O-trans-caffeoylquinic acid;CRYPTOCHLOROGENIC ACID (4-CQA)
- CBNumber:
- CB81040700
- Molecular Formula:
- C16H18O9
- Molecular Weight:
- 354.31
- MDL Number:
- MFCD10566638
- MOL File:
- 905-99-7.mol
- MSDS File:
- SDS
| Boiling point | 694.9±55.0 °C(Predicted) |
|---|---|
| Density | 1.65 |
| storage temp. | 2-8°C |
| solubility | DMSO : 50 mg/mL (141.12 mM; Need ultrasonic) |
| pka | 4.07±0.50(Predicted) |
| form | Solid |
| color | White-pale yellow |
| optical activity | [α]/D -76.0±5.0°, c = 0.5 in H2O |
| Stability | Hygroscopic |
| FDA UNII | F23DJ84IZ9 |
| UNSPSC Code | 85151701 |
| NACRES | NA.28 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
Cryptochlorogenic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 65969 | 4-O-Caffeoylquinic acid ≥98.0% | 905-99-7 | 10mg | $338 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL80393 | Cryptochlorogenic acid phyproof? Reference Substance | 905-99-7 | 10MG | $624 | 2024-03-01 | Buy |
| Sigma-Aldrich | 65969 | 4-O-Caffeoylquinic acid ≥98.0% | 905-99-7 | 50mg | $834 | 2024-03-01 | Buy |
| Cayman Chemical | 25098 | Cryptochlorogenic Acid ≥98% | 905-99-7 | 10mg | $146 | 2024-03-01 | Buy |
| Cayman Chemical | 25098 | Cryptochlorogenic Acid ≥98% | 905-99-7 | 50mg | $656 | 2024-03-01 | Buy |
Cryptochlorogenic acid Chemical Properties,Uses,Production
Uses
4-O-Caffeoylquinic acid has been used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).
Uses
Cryptochlorogenic acid may be used as a reference standard in the determination of cryptochlorogenic acid in the leaves of Hibiscus sabdariffa using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS).
Definition
ChEBI: A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 4-hydroxy group of (+)-quinic acid.
General Description
Cryptochlorogenic acid is a polyphenol, found in a variety of plants, which plays a crucial role in protection against various age-related diseases.
Biochem/physiol Actions
4-O-Caffeoylquinic acid (4-CQA) is a major active antioxidant marker in mulberry leaf extract. It is an inhibitor of ferroptosis hence, it is recognized as a potent anti-diabetic agent. 4-CQA plays an important role in the upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway.
in vivo
Pharmacokinetic parameters of Cryptochlorogenic acid after intragastric administration of Cryptochlorogenic acid at three dosages[2]
| Dose (mg/kg) | Cmax (μg/L) | tmax (h) | t1/2 (h) | AUC0-t (μg?h/L) | AUC0-∞ (μg?h/L) | MRT0-t (h) | MRT0-∞ (h) |
| 100 | 630 | 0.33 | 2.00 | 1938.91 | 1977.70 | 3.21 | 3.51 |
| 200 | 1270.09 | 0.47 | 1.97 | 3071.87 | 3179.41 | 3.23 | 3.39 |
| 400 | 2582.68 | 0.44 | 2.34 | 8825.32 | 9139.54 | 3.47 | 3.93 |
IC 50
HIF-1α
Cryptochlorogenic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3883 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 953 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
View Lastest Price from Cryptochlorogenic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Cryptochlorogenic acid
905-99-7
|
US $57.00 / mL | 99.67% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-08-25 | Cryptochlorogenic acid
905-99-7
|
US $0.00-0.00 / KG | 1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2023-02-24 | Cryptochlorogenic acid
905-99-7
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Cryptochlorogenic acid
905-99-7
- US $57.00 / mL
- 99.67%
- TargetMol Chemicals Inc.
-
- Cryptochlorogenic acid
905-99-7
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Cryptochlorogenic acid
905-99-7
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.