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illudin S

illudin S Structure
illudin S structure
CAS No.
1149-99-1
Chemical Name:
illudin S
Synonyms
CS-1385;Illudin;Lampterol;Illusin S;Lunamycin;illudin S;NSC 400979;Illudine S;NSC-626369;(1R,2S,5R)-1,5-dihydroxy-2-(hydroxymethyl)-2,5,7-trimethylspiro[1H-indene-6,1'-cyclopropane]-4-one
CBNumber:
CB91318110
Molecular Formula:
C15H20O4
Molecular Weight:
264.32
MDL Number:
MFCD00870487
MOL File:
1149-99-1.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33
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illudin S Properties

Melting point 124-126℃
Boiling point 327.55°C (rough estimate)
Density 1.0583 (rough estimate)
refractive index 1.4300 (estimate)
storage temp. -20°C, Inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form A light yellow solid
pka 12.50±0.70(Predicted)
color Off-white to yellow
FDA UNII EWJ0GY2H7X

illudin S price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17451 Illudin S ≥98% 1149-99-1 1mg $303 2024-03-01 Buy
Cayman Chemical 17451 Illudin S ≥98% 1149-99-1 5mg $1208 2024-03-01 Buy
ApexBio Technology C4732 IlludinS 1149-99-1 5mg $1381 2021-12-16 Buy
ApexBio Technology C4732 IlludinS 1149-99-1 1mg $345 2021-12-16 Buy
American Custom Chemicals Corporation INB0003821 ILLUDIN S 95.00% 1149-99-1 5MG $495.42 2021-12-16 Buy
Product number Packaging Price Buy
17451 1mg $303 Buy
17451 5mg $1208 Buy
C4732 5mg $1381 Buy
C4732 1mg $345 Buy
INB0003821 5MG $495.42 Buy

illudin S Chemical Properties,Uses,Production

Description

Illudins are fungal sesquiterpenes that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin , epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents.

Uses

Illudin S is a potent antitumor sesquiterpene.

Uses

Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive metabolites. Importantly, illudin S exhibits in vitro and in vivo potency against multi-drug resistant tumours.

Definition

ChEBI: Illudin S is a sesquiterpenoid.

illudin S Preparation Products And Raw materials

Raw materials

Preparation Products

illudin S Suppliers

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Zhejiang Huida Biotech Co., LTD 		008613515763466 8615669048680 wendy@huidabiotech.com CHINA 87 58
Shanghai Minbiotech Co., Ltd. 		+8617315815539 sales@minbiotech.com CHINA 129 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15352 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
BOC Sciences 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
TargetMol Chemicals Inc. 		58
Zhejiang Huida Biotech Co., LTD 		58
Shanghai Minbiotech Co., Ltd. 		58
AFINE CHEMICALS LIMITED 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58

View Lastest Price from illudin S manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
illudin S pictures 2025-02-05 illudin S
1149-99-1
 US $0.00 / kg 20kg 99% 20 tons Qingdao RENAS Polymer Material Co., Ltd.
Illudin S pictures 2024-11-19 Illudin S
1149-99-1
 US $157.00-561.00 / mg 98.15% 10g TargetMol Chemicals Inc.
illudin S pictures 2024-08-18 illudin S
1149-99-1
 US $0.00-0.00 / KG 1KG 99.0% 10 tons Shaanxi Dideu Medichem Co. Ltd
  • illudin S pictures
  • illudin S
    1149-99-1
  • US $0.00 / kg
  • 99%
  • Qingdao RENAS Polymer Material Co., Ltd.
  • Illudin S pictures
  • Illudin S
    1149-99-1
  • US $157.00-561.00 / mg
  • 98.15%
  • TargetMol Chemicals Inc.
  • illudin S pictures
  • illudin S
    1149-99-1
  • US $0.00-0.00 / KG
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd

illudin S Spectrum

illudin S(1149-99-1)1HNMR

1149-99-1(illudin S)Related Search:

PROTOPANAXDIOL Lupeol Quillaic acid Cryptochlorogenic acid Cryptotanshinone
DEMETON S illudin M (S)-1-CYCLOPROPYLETHANOL FEMA 3766 1-CYCLOPROPYL-PROPAN-2-ONE
3-METHYL-3-CYCLOHEXEN-1-ONE 2,2,4,6,6-PENTAMETHYL-3-HEPTENE illudin S 1-CYCLOPROPYL-1-METHYLETHANOL 3,5,5-trimethylcyclohex-3-en-1-one
1-(1-METHYLCYCLOPROPYL)ACETONE ISO-PROPENYLCYCLOPROPANE

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illudin S (2'S,3'R,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2'-hydroxymethyl-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one Illusin S Lampterol NSC-626369 Illudin Illudine S Lunamycin NSC 400979 (1R,2S,5R)-1,5-dihydroxy-2-(hydroxymethyl)-2,5,7-trimethylspiro[1H-indene-6,1'-cyclopropane]-4-one CS-1385 Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-, (2'S,3'R,6'R)- (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-one 1149-99-1 ADC