일루딘S
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일루딘S 속성
- 녹는점
- 124-126℃
- 끓는 점
- 327.55°C (rough estimate)
- 밀도
- 1.0583 (rough estimate)
- 굴절률
- 1.4300 (estimate)
- 저장 조건
- -20°C, Inert atmosphere
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- A light yellow solid
- 산도 계수 (pKa)
- 12.50±0.70(Predicted)
- 색상
- Off-white to yellow
안전
일루딘S C화학적 특성, 용도, 생산
개요
Illudins are fungal sesquiterpenes that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin , epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents.용도
Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive metabolites. Importantly, illudin S exhibits in vitro and in vivo potency against multi-drug resistant tumours.일루딘S 준비 용품 및 원자재
원자재
준비 용품
일루딘S 공급 업체
글로벌( 76)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3878 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 |
contact@fuxinpharm.com | China | 10297 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 |
wendy@huidabiotech.com | CHINA | 87 | 58 |
Shanghai Minbiotech Co., Ltd. | +8617315815539 |
sales@minbiotech.com | CHINA | 129 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15395 | 58 |
Henan Alfa Chemical Co., Ltd | +8618339805032 |
alfa4@alfachem.cn | China | 13183 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 |
sales@chemhifuture.com | China | 3136 | 58 |
일루딘S 관련 검색:
3,5,5-트라이메틸-3-사이클로헥센-1-온
PROTOPANAXDIOL
Lupeol
Quillaic acid
Cryptochlorogenic acid
Cryptotanshinone
DEMETON S
illudin M
(S)-1-CYCLOPROPYLETHANOL
FEMA 3766
1-CYCLOPROPYL-PROPAN-2-ONE
3-METHYL-3-CYCLOHEXEN-1-ONE
2,2,4,6,6-PENTAMETHYL-3-HEPTENE
illudin S
1-CYCLOPROPYL-1-METHYLETHANOL
1-(1-METHYLCYCLOPROPYL)ACETONE
ISO-PROPENYLCYCLOPROPANE