Pulmozyme
- CAS No.
- 143831-71-4
- Chemical Name:
- Pulmozyme
- Synonyms
- Pulmozyme;Unii-953A26oa1y;Dnase1 protein, human;Deoxyribonuclease I recombinant human form;1: PN: WO2007027578 PAGE: 17 claimed protein;Deoxyribonuclease (human clone 18-1 protein moiety);Nuclease, deoxyribo- (human clone 18-1 protein moiety)
- CBNumber:
- CB81179615
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD04113356
- MOL File:
- Mol file
| NCI Dictionary of Cancer Terms | Pulmozyme |
|---|---|
| FDA UNII | 953A26OA1Y |
| NCI Drug Dictionary | Pulmozyme |
Pulmozyme Chemical Properties,Uses,Production
Description
Dornase alfa, the highly purified solution of recombinant human deoxyribonuclease I (rhDNase) produced by genetic engineering technology, was launched in 1994 first in the U.S.A. and shortly after in 7 other countries as the first new drug released in 30 years for the treatment of cystic fibrosis. Dornase alfa is effective in liquefying secretions from the lungs of cystic fibrosis patients by cleaving the extracellular DNA in purulent sputum and therefore reducing the viscoelasticity of the secretion. It also lessens dyspnea, improves lung function, reduces cough severity and frequency, increases the perception of well-being for the patients with cystic fibrosis related symptoms, and has excellent safety profile. Significant benefits have been reported in trials for the treatment of chronic obstructive pulmonary disease and acute infectious exacerbation of chronic bronchitis.
Originator
Genentech (U.S.A.)
Uses
Cystic fibrosis therapy adjunct.
brand name
Pulmozyme (Genentech).
Pulmozyme Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Waterstone Technology, LLC | -- | sales@waterstonetech.com | United States | 6801 | 30 |
| Lanospharma Laboratories Co.,Ltd | -- | sales@lanospharma.com | China | 6343 | 56 |
| Supplier | Advantage |
|---|---|
| Waterstone Technology, LLC | 30 |
| Lanospharma Laboratories Co.,Ltd | 56 |
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