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FOSFOMYCIN SODIUM

CAS No.
23519-26-8
Chemical Name:
FOSFOMYCIN SODIUM
Synonyms
[4-[(E)-4-(4-phosphonatooxyphenyl)hex-3-en-3-yl]phenyl] phosphate;tetrasodium (3E)-hex-3-ene-3,4-diyldibenzene-4,1-diyl bis(phosphate)
CBNumber:
CB81264878
Molecular Formula:
C18H18Na4O8P2
Molecular Weight:
516.237322
MDL Number:
MFCD17215669
MOL File:
23519-26-8.mol
MSDS File:
SDS
Last updated:2023-05-09 09:30:52

FOSFOMYCIN SODIUM Properties

FDA UNII G9I1882VSD

FOSFOMYCIN SODIUM Chemical Properties,Uses,Production

Originator

Stilphostrol,Dome,US,1955

Uses

Estrogen.

Manufacturing Process

A solution of 1 part of α,α'-diethyl-4,4'-dihydroxystilbene in 5 parts of pyridine is added drop by drop to the strongly cooled solution of 2 parts of phosphorus-hydroxy chloride in 5 parts of pyridine. The mixture soon solidifies to a crystalline magma. It is allowed to stand in ice for ? hour and then for an hour at room temperature. The mass is then poured into an excess of saturated sodium bicarbonate solution. Unconsumed parent material is removed by extraction with ether. The aqueous solution is then mixed with 2 N hydrochloric acid, whereupon the primary phosphoric acid ester of α,α'- diethyl-4,4'-dihydroxystilbene of the formula is precipitated in the form of a voluminous white powder. By recrystallization or reprecipitation this ester may be further purified.

Therapeutic Function

Estrogen, Antitumor

FOSFOMYCIN SODIUM Preparation Products And Raw materials

Raw materials

Preparation Products

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[4-[(E)-4-(4-phosphonatooxyphenyl)hex-3-en-3-yl]phenyl] phosphate tetrasodium (3E)-hex-3-ene-3,4-diyldibenzene-4,1-diyl bis(phosphate) 23519-26-8