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INDEX NAME NOT YET ASSIGNED

INDEX NAME NOT YET ASSIGNED Structure
INDEX NAME NOT YET ASSIGNED structure
CAS No.
2749628-17-7
Chemical Name:
INDEX NAME NOT YET ASSIGNED
Synonyms
CBNumber:
CB812803752
Molecular Formula:
C17H19N3O4S
Molecular Weight:
361.42
MDL Number:
MOL File:
2749628-17-7.mol
Last updated:2023-06-08 09:03:09
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INDEX NAME NOT YET ASSIGNED Properties

solubility Chloroform: slightly soluble; Methanol: slightly, heated
form A solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

INDEX NAME NOT YET ASSIGNED price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26784 Omeprazole sulfone-d3 ≥99% deuterated forms (d1-d3) 2749628-17-7 500 μg $158 2024-03-01 Buy
Cayman Chemical 26784 Omeprazole sulfone-d3 ≥99% deuterated forms (d1-d3) 2749628-17-7 1 mg $299 2024-03-01 Buy
Product number Packaging Price Buy
26784 500 μg $158 Buy
26784 1 mg $299 Buy

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Description

Omeprazole sulfone-d3 is intended for use as an internal standard for the quantification of omeprazole sulfone by GC- or LC-MS. Omeprazole sulfone is the major metabolite of the gastric proton pump inhibitor, omeprazole . It is produced by cytochrome P450 (CYP)3A4 sulfoxidation of esomeprazole magnesium and is found in plasma.1 Omeprazole sulfone has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 18 μM).2

References

1. ?bel?, A., Andersson, T.B., Antonsson, M., et al. Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes Drug Metab. Dispos. 28(8),966-972(2000).
2. Ogilvie, B.W., Yerino, P., Kazmi, F., et al. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: Implications for coadministration with clopidogrel Drug Metab. Dispos. 39(11),2020-2033(2011).

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Supplier Advantage
Shanghai Yifei Biotechnology Co. , Ltd. 58
2749628-17-7