KY 234
- CAS No.
- 172544-75-1
- Chemical Name:
- KY 234
- Synonyms
- KY 234
- CBNumber:
- CB81306419
- Molecular Formula:
- C33H35N5O2.3ClH
- Molecular Weight:
- 643.055
- MDL Number:
- MFCD00917059
- MOL File:
- 172544-75-1.mol
KY 234 Chemical Properties,Uses,Production
Description
KY 234 is a thromboxane synthetase antagonist.
Uses
KY 234 is an orally effective inhibitor that targets thromboxane A2 production, with an IC50 of 5 μM. KY 234 significantly inhibits leukotriene D4 (LTD4), histamine, and antigen-induced bronchoconstriction in guinea pigs, with IC50 values of 6.0 mg/kg, 2.5 mg/kg, and 6.3 mg/kg, respectively[1].
References
[1] KAMIYA S, et al. Thromboxane A2 synthetase inhibitors with histamine H1-blocking activity: synthesis and evaluation of a new series of indole derivatives[J]. Chemical and pharmaceutical bulletin, 1995, 43(10): 1692-1695.
KY 234 Preparation Products And Raw materials
Raw materials
Preparation Products
KY 234 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19889 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19746 | 58 |
| Supplier | Advantage |
|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
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