olivetolic acid
- CAS No.
- 491-72-5
- Chemical Name:
- olivetolic acid
- Synonyms
- Olivetolcarboxylic acid;2,4-Dihydroxy-6-pentylbenzoic acid;139400;olivetolic acid;olivanic acid powder 98%;Olivetolic acid in Methanol;Benzoic acid, 2,4-dihydroxy-6-pentyl-;Olivetolic acid 1000 μg/mL in Methanol
- CBNumber:
- CB81340565
- Molecular Formula:
- C12H16O4
- Molecular Weight:
- 224.25
- MDL Number:
- MFCD28383644
- MOL File:
- 491-72-5.mol
- MSDS File:
- SDS
| Melting point | 143 °C |
|---|---|
| Boiling point | 403.9±25.0 °C(Predicted) |
| Density | 1.237±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.41±0.34(Predicted) |
| color | Light Beige to Light Brown |
| Stability | Hygroscopic |
| InChI | InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16) |
| InChIKey | SXFKFRRXJUJGSS-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=C(CCCCC)C=C(O)C=C1O |
| FDA UNII | 3Y8J575L93 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H319-H317 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P272-P280-P301+P312-P330-P302+P352-P304+P340-P305+P351+P338-P362+P364-P333+P313-P321-P337+P313-P363-P501 | |||||||||
| NFPA 704 |
|
olivetolic acid price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26282 | Olivetolic Acid | 491-72-5 | 25mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 26282 | Olivetolic Acid | 491-72-5 | 5mg | $31 | 2023-06-20 | Buy |
| TRC | O533005 | OlivetolicAcid | 491-72-5 | 100mg | $180 | 2021-12-16 | Buy |
| TRC | O533005 | OlivetolicAcid | 491-72-5 | 500mg | $490 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0005334 | OLIVETOLIC ACID 95.00% | 491-72-5 | 5MG | $501.01 | 2021-12-16 | Buy |
olivetolic acid Chemical Properties,Uses,Production
Uses
Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol.
Definition
ChEBI: A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively.
Biosynthesis
Olivetolic acid (OLA) biosynthesis involves the condensation of one hexanoyl-CoA with three malonyl-CoAs by a type III PKS (tetraketide synthase) OLA synthase (C. sativa OLS; CsOLS) and an OLA cyclase (CsOAC), both enzymes were derived from the Cannabis species (C. sativa). Studies have achieved trace amount of OLA production in both E. coli and S. cerevisia[1]. Ma et al. find that Pseudomonas sp LvaE encoding a short-chain acyl-CoA synthetase can efficiently convert hexanoic acid to hexanoyl-CoA. The co-expression of the acetyl-CoA carboxylase, the pyruvate dehydrogenase bypass, the NADPH-generating malic enzyme, as well as the activation of peroxisomal β-oxidation pathway and ATP export pathway are effective strategies to redirect carbon flux toward OLA synthesis.
References
[1] Ma, J, Y. Gu, and P. Xu . "Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica." Cold Spring Harbor Laboratory(2021).
olivetolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
olivetolic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Blazer Biomedical Technology Co., Ltd. | 0523-86112008 13915404123 | sales@blazerbio.com | China | 88 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 2998 | 58 |
| Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | info@pharmachemm.com | China | 251 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3003 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11775 | 58 |
View Lastest Price from olivetolic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-26 | olivetolic acid
491-72-5
|
US $0.00-0.00 / kg | 1kg | 99% | 3000kg | Jinan Jianfeng Chemical Co., Ltd | |
 |
2024-11-19 | Olivetolic acid
491-72-5
|
US $195.00-692.00 / mg | 99.72% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-07-17 | olivetolic acid
491-72-5
|
US $1.00-50.00 / KG | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- olivetolic acid
491-72-5
- US $0.00-0.00 / kg
- 99%
- Jinan Jianfeng Chemical Co., Ltd
-
- Olivetolic acid
491-72-5
- US $195.00-692.00 / mg
- 99.72%
- TargetMol Chemicals Inc.
-
- olivetolic acid
491-72-5
- US $1.00-50.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd