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2-Hydroxypyridine

2-Hydroxypyridine structure

CAS No.: 142-08-5

Chemical Name:: 2-Hydroxypyridine

Synonyms: Pyridin-2(1H)-one;2-PYRIDONE;2(1h)-pyridinone;2-Pyridinol;Pyridin-2-one;2(1H)-PYRIDONE;2-PYRIDON;2-PYRIDOL;Pyridone-2;A-PYRIDONE

CBNumber:: CB8137755

Molecular Formula:: C5H5NO

Molecular Weight:: 95.1

MDL Number:: MFCD00006268

MOL File:: 142-08-5.mol

MSDS File:: SDS

Last updated:2024-12-18 14:15:32

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2-Hydroxypyridine Properties

Melting point	105-107 °C (lit.)
Boiling point	280-281 °C (lit.)
Density	1.39
refractive index	1.5939 (estimate)
Flash point	210 °C
storage temp.	Sealed in dry,Room Temperature
solubility	450g/l
pka	0.75(at 20℃)
form	Liquid
color	Colorless to yellow to brown, darken on storage with no loss of purity
Water Solubility	Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
BRN	105786
LogP	-0.593 (est)
CAS DataBase Reference	142-08-5(CAS DataBase Reference)
FDA UNII	6770O3A2I5
NIST Chemistry Reference	2(1H)-Pyridinone(142-08-5)
EPA Substance Registry System	2(1H)-Pyridinone (142-08-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

P301+P330+P331+P310

Hazard Codes

Xi,Xn,T

Risk Statements

36/37/38-40-25

Safety Statements

26-36-37/39-22-45-36/37/39

RIDADR

UN2811

WGK Germany

RTECS

UV1144050

TSCA

Yes

HazardClass

6.1

PackingGroup

III

HS Code

29333990

Toxicity

LD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85

NFPA 704

	1
2		0

2-Hydroxypyridine price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H56800	2-Hydroxypyridine 97%	142-08-5	25g	$53.9	2024-03-01	Buy
Sigma-Aldrich	41152	2-Hydroxypyridine analytical standard	142-08-5	100mg	$67.2	2022-05-15	Buy
TCI Chemical	H0330	2-Hydroxypyridine >98.0%(GC)(T)	142-08-5	25g	$37	2024-03-01	Buy
TCI Chemical	H0330	2-Hydroxypyridine >98.0%(GC)(T)	142-08-5	250g	$267	2024-03-01	Buy
Alfa Aesar	A14522	2-Hydroxypyridine, 98%	142-08-5	25g	$42.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
H56800	25g	$53.9	Buy
41152	100mg	$67.2	Buy
H0330	25g	$37	Buy
H0330	250g	$267	Buy
A14522	25g	$42.65	Buy

2-Hydroxypyridine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal

Uses

2-Hydroxypyridine is a bifunctional catalyst for a wide variety of acylation reactions, catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. It is used in peptide synthesis.

Uses

Catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.

Definition

ChEBI: 2-Hydroxypyridine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. It has a role as a plant metabolite.

General Description

2-Hydroxypyridine, an enolic tautomer of 2-pyridone, belongs to the class of volatile organic compounds (VOCs).

Safety Profile

Moderately toxic by intraperitoneal and intravenous routes. A combustible liquid. When heated to decomposition it emits toxic vapors of NOx.

Purification Methods

Distil the pyridone under vacuum to remove coloured impurity, then recrystallise from *benzene, CCl4, EtOH or CHCl3/diethyl ether. It can be sublimed under high vacuum. [DePue et al. J Am Chem Soc 107 2131 1985, Beilstein 21/7 V 106.]

2-Hydroxypyridine synthesis

Synthesis of 2-Hydroxypyridine from Piperidine and Hexylamine and Ethyl cyanoacetate and Ethyl 4,4,4-trifluoroacetoacetate

2-Hydroxypyridine Preparation Products And Raw materials

Raw materials

1,3-Dicyclohexylthiourea Allyl isothiocyanate Dicyclohexylcarbodiimide Carbonic acid, 1,1-dimethylethyl 2-pyridinyl ester (9CI) 2(1H)-Pyridinone, 1-[[(4-methoxy-1-naphthalenyl)carbonyl]oxy]- (9CI)

BOC-L-Tyrosine

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Preparation Products

DI-2-PYRIDYL THIONOCARBONATE Reactive Brilliant Yellow M-7G 2-Hydroxy-5-bromopyridine 5-CHLOROPYRIDIN-2(1H)-ONE disodium 4-[[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl]azo]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzene-1,3-disulphonate

3,5-DICHLORO-2-PYRIDONE 2,3-Dihydroxypyridine (2-OXOPYRIDIN-1(2H)-YL)ACETIC ACID 2-HYDRAZINO-3-NITROPYRIDINE

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2-Hydroxypyridine Suppliers

Global( 590)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Wisdom Chemicals Co., Ltd.	+8613701363759	market@wisdomchem.com	China	254	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12834	58
JINING XINHE CHEMICAL CO., LTD	+8615318402391	sales@xinhepharma.com	China	809	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2986	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58

Supplier	Advantage
Beijing Wisdom Chemicals Co., Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
JINING XINHE CHEMICAL CO., LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Standardpharm Co. Ltd.	58

View Lastest Price from 2-Hydroxypyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-12-13	2-Hydroxypyridine 142-08-5	US $0.00-0.00 / kg	1kg	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2024-11-19	α-Pyridone 142-08-5	US $48.00 / mg		99.96%	10g	TargetMol Chemicals Inc.
2024-07-21	2-Hydroxypyridine 142-08-5	US $0.00-0.00 / kg	1kg	99%	10ton	JINING XINHE CHEMICAL CO., LTD

2-Hydroxypyridine
142-08-5
US $0.00-0.00 / kg
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

α-Pyridone
142-08-5
US $48.00 / mg
99.96%
TargetMol Chemicals Inc.

2-Hydroxypyridine
142-08-5
US $0.00-0.00 / kg
99%
JINING XINHE CHEMICAL CO., LTD

2-Hydroxypyridine Spectrum

2-Hydroxypyridine(142-08-5)MS 2-Hydroxypyridine(142-08-5)¹HNMR 2-Hydroxypyridine(142-08-5)¹³CNMR 2-Hydroxypyridine(142-08-5)IR1 2-Hydroxypyridine(142-08-5)IR2 2-Hydroxypyridine(142-08-5)Raman

142-08-5(2-Hydroxypyridine)Related Search:

Hydroxy silicone oil 4-Methylpyridine (+/-)-NICOTINE 2,3,4-Trihydroxybenzoic acid 2-(Hydroxymethyl)pyridine

2-Chloro-5-chloromethylpyridine Sulfasalazine 2,5-Dimethylpyridine Chromium picolinate 4-Hydroxypyridine

Pyridin-2-ol Levetiracetam impurity 8 Levetiracetam acid LevetiracetaM IMpurity B (S)-N-(1-aMino-1-oxobutan-2-yl)-4-chlorobutanaMide

alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid Levetiracetam impurity 6 Levetiracetam

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1-Hydroxy-2-pyridine alpha-Pyridone Pyridone-2 AURORA KA-3075 A-PYRIDONE TIMTEC-BB SBB004392 a-Hydroxypyridine 1,2-dihydro-2-oxopyridine 1H-2-Pyridone 1h-pyridin-2-one 2-pyridinone 2-PYRIDON 2-PYRIDOL 2-oxopyridine 2-Pyridinol (2-hydroxy-pyridin) 2-hydroxypyridine (intermediate of benzoxazole) Diydrozylpyridine 2-Hydroxypyridine(2-Pyridinol) 2-Hydroxypyridine 2-Hydroxypyridine, 98+% 2-HYDROXYPYRIDINE pure 2-Pyridinol 2-Pyridone 2-PYRIDINOL FOR SYNTHESIS 2-hydroxypyridate 2(1H)-Pyridone, 2-Pyridinol 2-Hydroxypyridine,97% 2-Hydroxypyridine 97% 3-Fluoro-4-Methylbenzenethiol, >95% Levetiracetam EP Impurity C 2-Hydroxypyridine> 2-Hydroxypyridine, 98%, for synthesis Levetiracetam impurity C CRS 2-Hydroxypyridine ISO 9001：2015 REACH α-Pyridone α-Pyridone (Levetiracetam Impurity) Levetiracetam impurities520 Levetiracetam impurities12 Levetiracetam-3 Levetiracetam Impurity 3（Levetiracetam EP Impurity C） 2(1h)-pyridinone 2(1H)-PYRIDONE 2-PYRIDONE 2-Pyridinol Pyridin-2(1H)-one Pyridin-2-one 2-HYDROXYPYRIDINE (2(1H)-Pyridinol) >98% 142-08-5 2762-00-6 148-08-5 C5H4NOH C5H5NO Building Blocks C5 Pyridines Heterocyclic Building Blocks Others Pyridines Pyridine