ChemicalBook >> CAS DataBase List >>polymyxin B(1)
polymyxin B(1)
- CAS No.
- 4135-11-9
- Chemical Name:
- polymyxin B(1)
- Synonyms
- polymyxin B(1);Polymyxin B1-[13C6,15N] TFA salt;Glucosamine Hydrochloride Impurity 33;polymyxin B1Q: What is polymyxin B1 Q: What is the CAS Number of polymyxin B1;(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-);(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide
- CBNumber:
- CB81388907
- Molecular Formula:
- C56H98N16O13
- Molecular Weight:
- 1203.48
- MDL Number:
- MFCD01699017
- MOL File:
- 4135-11-9.mol
Last updated:2025-04-17 18:22:24
| Boiling point | 838.79°C (rough estimate) |
|---|---|
| Density | 1.0500 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | Store at -20°C |
| solubility | PBS (pH 7.2): 2 mg/ml |
| form | A crystalline solid |
| pka | 13.08±0.70(Predicted) |
| color | White to off-white |
| FDA UNII | B35S89JSRU |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
polymyxin B(1) price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14074 | Polymyxin B1 ≥95% | 4135-11-9 | 1mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 14074 | Polymyxin B1 ≥95% | 4135-11-9 | 5mg | $477 | 2024-03-01 | Buy |
| Cayman Chemical | 14074 | Polymyxin B1 ≥95% | 4135-11-9 | 10mg | $759 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0013125 | POLYMYXIN B(1) 95.00% | 4135-11-9 | 5MG | $501.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013125 | POLYMYXIN B(1) 95.00% | 4135-11-9 | 1MG | $225.75 | 2021-12-16 | Buy |
polymyxin B(1) Chemical Properties,Uses,Production
Uses
An antibacterial compound. It has a high volume of distribution and longer elimination half-life in patient with multidrug-resistant gram-negative bacterial infection.
Definition
ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus.
in vivo
The pharmacokinetics of Polymyxin B1 is investigated in a rat model following intravenous administration (0.8 mg/kg). The area under the concentration-time curve for Polymyxins B1 is greater than those of colistins A and B. Colistin A colistin B. The clearance value of Polymyxins B1 is 2.39 mL/min/kg, the plasma protein binding is 82.3%, the elimination half-life is 79.5 min and the AUC0-∞ is 365 mg min/L[5].
polymyxin B(1) Preparation Products And Raw materials
Raw materials
Preparation Products
polymyxin B(1) Suppliers
Global( 62)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3003 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Guangzhou CATO Research Chemicals Inc. | +86-020-81960175-617 +8615602392859 | Intermediate@cato-chem.com | China | 6335 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5222 | 58 |
| Moxin Chemicals | +8617320513646 | mike@molcoo.com | China | 9711 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | 0755-66853366; 13670046396 | ORDERS@QCSRM.COM | China | 24342 | 58 |
| Guangzhou PI PI Biotech Inc | 020-81716320 +86-13602409664 | Sales@pipitech.com | China | 3633 | 55 |
View Lastest Price from polymyxin B(1) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Polymyxin B1
4135-11-9
|
US $1190.00-1890.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-05-18 | polymyxin B(1)
4135-11-9
|
US $1.00-60.00 / KG | 1KG | 99%+ | 10086KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-04-10 | Polymyxin B1
4135-11-9
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC |
-
- Polymyxin B1
4135-11-9
- US $1190.00-1890.00 / mg
- TargetMol Chemicals Inc.
-
- polymyxin B(1)
4135-11-9
- US $1.00-60.00 / KG
- 99%+
- Shaanxi Dideu Medichem Co. Ltd
-
- Polymyxin B1
4135-11-9
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
4135-11-9(polymyxin B(1))Related Search:
polymyxin B(1)
(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)
(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide
polymyxin B1Q: What is
polymyxin B1 Q: What is the CAS Number of
polymyxin B1
(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
Polymyxin B1-[13C6,15N] TFA salt
Glucosamine Hydrochloride Impurity 33
4135-11-9
14135-11-9
C56H98N16O13