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ChemicalBook >> CAS DataBase List >> polymyxin B(1)

polymyxin B(1)

polymyxin B(1) price.
  • $120 - $759
  • Product name: polymyxin B(1)
  • CAS: 4135-11-9
  • MF: C56H98N16O13
  • MW: 1203.48
  • EINECS:
  • MDL Number:MFCD01699017
  • Synonyms:polymyxin B(1);(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-);(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;polymyxin B1Q: What is polymyxin B1 Q: What is the CAS Number of polymyxin B1;(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;Polymyxin B1-[13C6,15N] TFA salt;Glucosamine Hydrochloride Impurity 33
6 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
Package
  • 1MG
  • 5MG
  • 10mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013125
  • Product descriptionPOLYMYXIN B(1) 95.00%
  • Packaging1MG
  • Price$225.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013125
  • Product descriptionPOLYMYXIN B(1) 95.00%
  • Packaging5MG
  • Price$501.05
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14074
  • Product descriptionPolymyxin B1 ≥95%
  • Packaging1mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14074
  • Product descriptionPolymyxin B1 ≥95%
  • Packaging5mg
  • Price$477
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14074
  • Product descriptionPolymyxin B1 ≥95%
  • Packaging10mg
  • Price$759
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019929
  • Product descriptionPolymyxinB1 ≥96.0%
  • Packaging1mg
  • Price$450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0013125 POLYMYXIN B(1) 95.00% 1MG $225.75 2021-12-16 Buy
American Custom Chemicals Corporation API0013125 POLYMYXIN B(1) 95.00% 5MG $501.05 2021-12-16 Buy
Cayman Chemical 14074 Polymyxin B1 ≥95% 1mg $120 2024-03-01 Buy
Cayman Chemical 14074 Polymyxin B1 ≥95% 5mg $477 2024-03-01 Buy
Cayman Chemical 14074 Polymyxin B1 ≥95% 10mg $759 2024-03-01 Buy
ChemScene CS-0019929 PolymyxinB1 ≥96.0% 1mg $450 2021-12-16 Buy

Properties

Boiling point :838.79°C (rough estimate)
Density :1.0500 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Store at -20°C
solubility :PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
pka :13.08±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 is a form of polymyxin B which terminates with 6-methyloctanamide. Polymyxin B1 is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity have not been examined.

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