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Acrichin dihydrochloride

CAS No.
69-44-3
Chemical Name:
Acrichin dihydrochloride
Synonyms
AMODIAQUINE HCL;camoquinhydrochloride;Amodiaquine HCL USP31;AMODIAQUIN HYDROCHLORIDE;Acrichin dihydrochloride;Amodiquine hydrochloride;AMODIAQUINE HYDROCHLORIDE;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE DIHYDROCHLORIDE;BULK DRUG : AMODIAQUINE HYDROCHLORIDE (DMF GRADE)
CBNumber:
CB8156037
Molecular Formula:
C20H23Cl2N3O
Molecular Weight:
392.32
MDL Number:
MFCD00078857
MOL File:
69-44-3.mol
Last updated:2024-07-02 08:55:18

Acrichin dihydrochloride Properties

storage temp. Sealed in dry,Room Temperature
solubility DMSO: 125 mg/mL (291.52 mM)
form Solid
color Light yellow to yellow
FDA UNII HOE64181MP

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
WGK Germany  3

Acrichin dihydrochloride price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C429303 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenolDihydrochloride 69-44-3 10mg $45 2021-12-16 Buy
ApexBio Technology C7157 Amodiaquine hydrochloride 69-44-3 100mg $50 2021-12-16 Buy
ChemScene CS-0013341 Amodiaquine(dihydrochloride) ≥98.0% 69-44-3 100mg $50 2021-12-16 Buy
Matrix Scientific 099311 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)-methyl)phenol dihydrochloride 95+% 69-44-3 10g $10 2021-12-16 Buy
ApexBio Technology C7157 Amodiaquine hydrochloride 69-44-3 200mg $80 2021-12-16 Buy
Product number Packaging Price Buy
C429303 10mg $45 Buy
C7157 100mg $50 Buy
CS-0013341 100mg $50 Buy
099311 10g $10 Buy
C7157 200mg $80 Buy

Acrichin dihydrochloride Chemical Properties,Uses,Production

Chemical Properties

Yellow crystalline solid; odorless; bitter. Soluble in water; sparingly soluble in alcohol; very slightly soluble in benzene, chloroform, and ether.

Originator

Camoquin HCl,Parke Davis,US,1950

Uses

Medicine (antimalarial).

Manufacturing Process

72.8 g (0.5 mol) of p-aminophenol hydrochloride is dissolved in 500 cc of water and added to 99 g (0.5 mol) of 4,7-dichloroquinoline. After a few minutes of warming in a steam bath, 4-(4'-hydroxyanilino)-7-chloroquinoline hydrochloride, of sufficient purity for use in further experiments, precipitates as a yellow crystalline solid. Recrystallized from methanol, the MP is over 300°C.
A mixture consisting of 13.5 g of 4-(4'-hydroxyanilino)-7-chloroquinoline hydrochloride dissolved in absolute ethanol is treated with a solution of 4.38 g of diethylamine and 1.8 g of paraformaldehyde in 20 cc of absolute ethanol. The reaction mixture is heated under reflux for 16 hours, evaporated to onehalf volume and the warm solution treated with an excess of hydrogen chloride dissolved in absolute ethanol. Acetone is added to the warm solution until it becomes turbid and then the solution is cooled. The crude dihydrochloride which separates is collected and purified by recrystallization from methanol; MP 240-242°C.
By using an equivalent amount of 4-(4'-hydroxyanilino)-7-bromoquinoline in the above procedure, 4-(3'-diethylaminomethyl-4'-hydroxyanilino)-7- bromoquinoline dihydrochloride is obtained; MP (base) 206-208°C dec.

brand name

Camoquin (Parke-Davis).

Therapeutic Function

Antimalarial

Acrichin dihydrochloride Preparation Products And Raw materials

Global( 156)Suppliers
Supplier Tel Email Country ProdList Advantage
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 973 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
career henan chemical co
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.GZ HONESTCHEM CO.,LTD
+86-15013270415 +86-15013270415 honestchemical@foxmail.com China 244 58
Xiamen AmoyChem Co., Ltd
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Chongqing Chemdad Co., Ltd
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
zhangjiagang vinsce bio-pharm. limited.
86-512-58389969 sales1@swellxin.com CHINA 111 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58

View Lastest Price from Acrichin dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acrichin dihydrochloride pictures 2024-11-22 Acrichin dihydrochloride
69-44-3
US $0.00 / Kg/Drum 25KG 97%-103%; USP 500kg WUHAN FORTUNA CHEMICAL CO., LTD
 Acrichin dihydrochloride pictures 2024-10-23 Acrichin dihydrochloride
69-44-3
US $1.00 / g 300g 99.8% 20 TONS .GZ HONESTCHEM CO.,LTD
Acrichin dihydrochloride pictures 2023-09-07 Acrichin dihydrochloride
69-44-3
US $30.00 / kg 1kg 99% 1000t/year Anhui Ruihan Technology Co., Ltd

Acrichin dihydrochloride Spectrum

4-[(7-CHLORO-4-QUINOLINYL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL DIHYDROCHLORIDE AMODIAQUIN DIHYDROCHLORIDE AMODIAQUIN HYDROCHLORIDE AMODIAQUINE HYDROCHLORIDE AMODIAQUINE HCL AMODIAQUINE DIHYDROCHLORIDE 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresodihydrochloride 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresoldihydrochloride camoquinhydrochloride 4-[(7-Chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol dihydrochloride 7-Chloro-4-(3'-diethylaminomethyl-4'-hydroxyanilino)quinoline dihydrochloride Acrichin dihydrochloride 4-[(7-chloro-4-quinolyl)amino]-2-(diethylaminomethyl)phenol dihydrochloride BULK DRUG : AMODIAQUINE HYDROCHLORIDE (DMF GRADE) Amodiaquine HCL USP31 Amodiquine hydrochloride 7-Chloro-4-(3'-diethylaminomethyl-4'-hydroxyanilino)quinoline dihydrochloride 69-44-3 C20H24Cl3N3O Alphabetic Analytical Chromatography Product Catalog AM to AQ Analytical Standards API 69-44-3