A[5']P5[5']A SODIUM SALT
- CAS No.
- 4097-04-5
- Chemical Name:
- A[5']P5[5']A SODIUM SALT
- Synonyms
- A(5′)P5(5′)A;A[5']P5[5']A SODIUM SALT;DIADENOSINE PENTAPHOSPHATE SODIUM SALT;Diadenosine pentaphosphate pentasodium;5'-ester with adenosine pentasodium salt;P1,P5-Di(adenosine-5;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATESOD IUM;Diadenosine pentaphosphate pentasodium salt;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE SODIUM SALT;P1,P5-di(adenosine-5')pentaphosphate pentasodium salt 5H2O
- CBNumber:
- CB8189688
- Molecular Formula:
- C20H24N10Na5O22P5
- Molecular Weight:
- 1026.28
- MDL Number:
- MFCD00077718
- MOL File:
- 4097-04-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
WGK Germany | 3 |
---|---|
F | 10-21 |
A[5']P5[5']A SODIUM SALT price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 2MG | $64.2 | 2023-06-20 | Buy |
Sigma-Aldrich | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 10MG | $158 | 2023-06-20 | Buy |
Sigma-Aldrich | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 25MG | $310 | 2023-06-20 | Buy |
Sigma-Aldrich | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 50MG | $557 | 2023-06-20 | Buy |
Usbiological | 296060 | Diadenosine pentaphosphate pentasodium salt | 4097-04-5 | 2mg | $347 | 2021-12-16 | Buy |
A[5']P5[5']A SODIUM SALT Chemical Properties,Uses,Production
Uses
P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt has been used as:
- an adenylate kinase (AK) inhibitor in: sarcoma osteogenic (Saos-2) cells
- mitochondrial lysates during ATP synthesis
- tetramethylrhodamine methyl ester (TMRM) based membrane potential assay
- chromoplasts
General Description
P1,P5-Di(adenosine-5′) pentaphosphate (Ap5A) is a diadenosine polyphosphate, which has a tail-to-tail dimer structure. Ap5A is synthesized in a twostep process involving the formation of adenosine 5′-tetraphosphate (P4A) from the ATP and trimeta-phosphate (P3). In the second step, P4A is converted to Ap5A. The synthesis of Ap5A requires a pH optimum in the range of 7.5 to 8.5 and is modulated by metal ions.
Biochem/physiol Actions
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.
A[5']P5[5']A SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
A[5']P5[5']A SODIUM SALT Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
BEST-REAGENT | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11726 | 57 |
9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22519 | 55 |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25013 | 65 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
Shandong Ono Chemical Co., Ltd. | 0539-6362799 20) | China | 10007 | 58 | |
Beijing OKA biological technology co., LTD | 010-010-010-62971590 18548936886 | jack@oka-vip.com | China | 6897 | 58 |
Shanghai kadel chemical technology co., LTD | 021-4007787-550 400-7787-550 | 2850202386@qq.com | China | 10599 | 58 |