(2S,3R,E)-2-Amino-4-icosene-1,3-diol
- CAS No.
- 6918-49-6
- Chemical Name:
- (2S,3R,E)-2-Amino-4-icosene-1,3-diol
- Synonyms
- C20-Sphingosine;Eicosaphingenine;Eicosasphingenine;Gangliosphingosine;Sphingosine (d20:1);20-Carbon-sphingosine;D-erythro-Sphingosine C-20;D-erythro-Sphingosine (d20:1);(2S,3R,4E)-4-Icosasphingenine;D-erythro-sphingosine (C20 base)
- CBNumber:
- CB82148391
- Molecular Formula:
- C20H41NO2
- Molecular Weight:
- 327.55
- MDL Number:
- MFCD08703032
- MOL File:
- 6918-49-6.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
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(2S,3R,E)-2-Amino-4-icosene-1,3-diol price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 07768 | (2S,3R,4E)-2-Amino-4-eicosene-1,3-diol ≥98.0% (TLC) | 6918-49-6 | 10mg | $203 | 2023-06-20 | Buy |
Sigma-Aldrich | 07768 | (2S,3R,4E)-2-Amino-4-eicosene-1,3-diol ≥98.0% (TLC) | 6918-49-6 | 50mg | $867 | 2023-01-07 | Buy |
Cayman Chemical | 10007903 | Sphingosine (d20:1) ≥98% | 6918-49-6 | 500μg | $33 | 2024-03-01 | Buy |
Cayman Chemical | 10007903 | Sphingosine (d20:1) ≥98% | 6918-49-6 | 1mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 10007903 | Sphingosine (d20:1) ≥98% | 6918-49-6 | 5mg | $176 | 2024-03-01 | Buy |
(2S,3R,E)-2-Amino-4-icosene-1,3-diol Chemical Properties,Uses,Production
Description
Sphingosines are long-
Uses
D-erythro-Sphingosine-C20 is an antagonist in cell-signaling functions however it displays an opposite modulation of cathepsin D.
Uses
Sphingosine (d20:1) has been used as a reference substance in liquid chromatography/tandem mass spectrometry analysis to quantitatively analyze sphingolipids with C20- long chain bases in human central nervous tissue.
Definition
ChEBI: C20 sphingosine is a sphingoid that is the C20 analogue of sphingosine. It has a role as a mouse metabolite. It is a sphingoid and an aminodiol. It is a conjugate base of a C20 sphingosine(1+).
General Description
Sphingosine (d20:1), also known as icosasphingosine, is a synthetic sphingosine with 20 carbon long chain bases (LCB). It is directly produced by the sphingolipid de novo synthesis pathway and not by hydrolysis of complex sphingolipids. In higher animals, it is one of the most abundant sphingoid bases of gangliosides.
Biochem/physiol Actions
Sphingosine (d20:1) or C20-sphingosine acts as an intermediate in the synthesis of ceramides, which are vital components of mammalian epidermis. It may be involved in regulation of epidermal differentiation. C20 long chain bases-containing sphingolipids might exhibit detrimental effect on protein homeostasis and neural functions.
(2S,3R,E)-2-Amino-4-icosene-1,3-diol Preparation Products And Raw materials
Raw materials
Preparation Products
(2S,3R,E)-2-Amino-4-icosene-1,3-diol Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18616739031 | 3007523370@qq.com | China | 52712 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 | malulu@leyan.com | China | 55023 | 58 |