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2,4-Dichloronitrobenzene

CAS No.
611-06-3
Chemical Name:
2,4-Dichloronitrobenzene
Synonyms
2,4-DICHLORO-1-NITROBENZENE;2,4-DCNB;2,4-Dichloroni;4-Dichloronitrobenzene;Bifeprunox Impurity 64;2,4-DICHLORONITROBENZENE;Nitro-2,4-dichlorobenzene;4-Nitro-m-dichlorobenzene;1,3-Dichlor-4-nitrobenzol;1,3-DICHLORO-4-NITROBENZENE
CBNumber:
CB8221355
Molecular Formula:
C6H3Cl2NO2
Molecular Weight:
192
MDL Number:
MFCD00007071
MOL File:
611-06-3.mol
Last updated:2023-10-20 16:42:24

2,4-Dichloronitrobenzene Properties

Melting point 29-32 °C(lit.)
Boiling point 258 °C(lit.)
Density 1.479
vapor pressure 0.013 hPa (20 °C)
refractive index 1.5512 (estimate)
Flash point >230 °F
storage temp. Store below +30°C.
solubility 188g/l
form Crystalline Low Melting Solid
color Yellow-brown
Water Solubility 188 mg/L (20 ºC)
BRN 1451655
Stability Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference 611-06-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 85P1A896RR
NIST Chemistry Reference Benzene, 2,4-dichloro-1-nitro-(611-06-3)
Proposition 65 List 2,4-Dichloro-1-Nitrobenzene
IARC 2B (Vol. 123) 2020
EPA Substance Registry System 2,4-Dichloronitrobenzene (611-06-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H311-H317-H341-H350-H411
Precautionary statements  P202-P273-P280-P301+P312-P302+P352+P312-P308+P313
Hazard Codes  Xi,N,Xn
Risk Statements  36/37/38-51/53-43-21/22
Safety Statements  26-36-61-36/37-24
RIDADR  2811
WGK Germany  3
RTECS  CZ5420000
Autoignition Temperature 500 °C
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29049085
Toxicity LD50 orally in Rabbit: 380 mg/kg LD50 dermal Rat 920 mg/kg
NFPA 704
1
1 0

2,4-Dichloronitrobenzene Chemical Properties,Uses,Production

Chemical Properties

yellow crystals

Uses

2,4-Dichloro-1-nitrobenzene is used as a reagent in the synthesis of the hepatitis C virus polymerase inhibitor, Deleobuvir (BI 207127).

Production Methods

1,3-Dichlorobenzene is nitrated with mixed acid, and the product 2,4-Dichloronitrobenzene is separated from the resulting isomer mixture.

General Description

Light yellow needles or amber crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Can react vigorously with oxidizing materials.

Fire Hazard

2,4-Dichloronitrobenzene is combustible.

2,4-DICHLORONITROBENZENE ASYM-NITRO-M-DICHLOROBENZENE 2,4-DICHLORONITROBENZENE PESTANAL, 250 M 2,4-DCNB Benzene, 2,4-dichloro-1-nitro- 1,3-Dichlor-4-nitrobenzol 4-Nitro-m-dichlorobenzene 1,3-Dichloro-4-nitrobenzene, asym.-Nitro-m-dichlorobenzene Nitro-2,4-dichlorobenzene 2,4-Dichloronitrobenzene,97% 4-Dichloronitrobenzene 1,3-DICHLORO-4-NITROBENZENE 2,4-Dichloroni 1,3-Dichloro-4-nitrobenzene for synthesis 1-Nitro-2,4-dichlorobenzene 2,4-dichloro-1-nitro-benzen Benzene, 1,3-dichloro-4-nitro 2,4-Dichloronitrobenzene > 1,3-DICHLORO-4-NITROBENZENE FOR SYNTHESI 2,4-DICHLORO-1-NITROBENZENE Bifeprunox Impurity 64 2,4-Dichloronitrobenzene, ≥ 99.0% 2,4-Dichloronitrobenzene Solution in Toluene C12432400 2,4-Dichloronitrobenzene 611-06-3 Nitrogen Compounds Organic Building Blocks Nitro Compounds Building Blocks Building Blocks Chemical Synthesis Nitro Compounds Nitrogen Compounds Organic Building Blocks Benzene derivates Chlorobenzene Series