(5α,12β,19α)-2,3-Didehydro-1-methylaspidospermidine-3-carboxylic acid methyl ester
- CAS No.
- 19074-77-2
- Chemical Name:
- (5α,12β,19α)-2,3-Didehydro-1-methylaspidospermidine-3-carboxylic acid methyl ester
- Synonyms
- Minovin;Minovine;(5α,12β,19α)-2,3-Didehydro-1-methylaspidospermidine-3-carboxylic acid methyl ester
- CBNumber:
- CB82266660
- Molecular Formula:
- C22H28N2O2
- Molecular Weight:
- 352.46992
- MDL Number:
- MOL File:
- 19074-77-2.mol
(5α,12β,19α)-2,3-Didehydro-1-methylaspidospermidine-3-carboxylic acid methyl ester Chemical Properties,Uses,Production
Description
A further alkaloid isolated from Vinca minor L., this base is possibly optically inactive, the specific rotation reported being [α]D 00 ± 2° (c 1.0, EtOH). The ultraviolet spectrum in EtOH has a broad absorption maximum at 338 mil and an inflexion at 310 mil. The structure has been confirmed by the synthesis of the (±)-form.
References
Kokry, Dubravkova, Sefecovic.,Experientia, 18,564 (1962)
Mokryetal., ibid, 19,311 (1963)
Zachystalova, Strouf, Trojanek., Chern. & Ind., 610 (1963)
Synthesis:
Kutney et al., J. Amer. Chern. Soc., 90,3891 (1968)
(5α,12β,19α)-2,3-Didehydro-1-methylaspidospermidine-3-carboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
(5α,12β,19α)-2,3-Didehydro-1-methylaspidospermidine-3-carboxylic acid methyl ester
Minovin
Minovine
19074-77-2