3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
- CAS No.
- 51225-30-0
- Chemical Name:
- 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
- Synonyms
- Wighteone;Erythrinin B;5,7,4'-Trihydroxy-6-prenylisoflavone;Erythrinin B|||6-Isopentenylgenistein;4',5,7-Trihydroxy-6-prenyl-isoflavone;4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone;5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one;5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
- CBNumber:
- CB82324582
- Molecular Formula:
- C20H18O5
- Molecular Weight:
- 338.35
- MDL Number:
- MFCD06796682
- MOL File:
- 51225-30-0.mol
Melting point | 227 °C(Solv: methanol (67-56-1)) |
---|---|
Boiling point | 586.1±50.0 °C(Predicted) |
Density | 1.351±0.06 g/cm3(Predicted) |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | powder |
pka | 7.03±0.20(Predicted) |
color | Yellow |
Stability | Light Sensitive |
FDA UNII | 48ZS74CB9A |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H310+H330-H302-H315-H319-H412 |
Precautionary statements | P501-P273-P260-P270-P262-P271-P264-P280-P284-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P312+P330-P302+P352+P310-P304+P340+P310-P403+P233-P405 |
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | W499205 | Wighteone | 51225-30-0 | 1mg | $70 | 2021-12-16 | Buy |
TRC | W499205 | Wighteone | 51225-30-0 | 5mg | $275 | 2021-12-16 | Buy |
TRC | W499205 | Wighteone | 51225-30-0 | 25mg | $935 | 2021-12-16 | Buy |
Biosynth Carbosynth | FW138624 | Wighteone | 51225-30-0 | 10mg | $1200 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0000273 | WIGHTEONE 95.00% | 51225-30-0 | 10G | $1334.03 | 2021-12-16 | Buy |
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Chemical Properties,Uses,Production
Uses
Wighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.
Definition
ChEBI: A member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 6. It has been isolated from Ficus mucuso.
target
HSP (e.g. HSP90) | Antifection
![446-72-0](/CAS/GIF/446-72-0.gif)
![51225-30-0](/CAS/GIF/51225-30-0.gif)
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9641 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5225 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
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