ANTI-APAF-1
- CAS No.
- Chemical Name:
- ANTI-APAF-1
- Synonyms
- Anti-DR3LG;Anti-APO3L;ANTI-APAF-1;ANTI-TNFSF 13;Anti-MGC20669;Anti-MGC129581;RABBIT ANTI-APAF-1;ANTI-APAF-1 (HUMAN);ANTI-TNFSF 13 (HUMAN);ANTI-A-PROLIFERATION-INDUCING LIGAND
- CBNumber:
- CB8245223
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02095846
- MOL File:
- Mol file
ANTI-APAF-1 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | WH0008742M1 | Monoclonal Anti-TNFSF12 antibody produced in mouse clone 4H3, purified immunoglobulin, buffered aqueous solution | 100μG | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA052967 | Anti-TNFSF12 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | GW21169 | Anti-APAF1 antibody produced in chicken affinity isolated antibody, buffered aqueous solution | 50μg | $405 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA052967 | Anti-TNFSF12 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy | |
| Sigma-Aldrich | SAB2102492 | Anti-TNFSF12 antibody produced in rabbit affinity isolated antibody | 100μL | $503 | 2023-01-07 | Buy |
ANTI-APAF-1 Chemical Properties,Uses,Production
Uses
Anti-APAF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
General Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. (provided by RefSeq)
Biochem/physiol Actions
Apoptotic protease activating factor 1 is a human homolog of C. elegans CED-4 gene and is a key regulator gene of apoptosis. It acts as a central component of the intrinsic pathway of apoptosis. Loss of APAF-1 expression is involved with chemorefractory malignant melanoma and neuronal cell differentiation. Over expression of this gene is related to an undifferentiated state in the testicular germ cell tumor (TGCT) pathway and is involved in carcinogenesis of germ cell tumors. APAF-1, when bound to cytochrome c, may trigger the activation of caspase-3 leading to apoptosis.
ANTI-APAF-1 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-APAF-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beinuo Biotechnology Co., Ltd. | -- | beinuobio@163.com | CHINA | 6580 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd. | -- | shybio@126.com | CHINA | 6969 | 58 |
| Beijing Bai Ao Si Biotechnology Co., Ltd. | -- | yangmei@bioneeds.net | CHINA | 6999 | 58 |
| Shenzhen Xinbosheng Biological Technology Co., Ltd. | -- | service@neobioscience.com | CHINA | 6164 | 58 |
| Shanghai Hao Biological Technology Co., Ltd. | -- | market@xlswkj.com | CHINA | 6805 | 58 |
| Shanghai Hao Biological Technology Co., Ltd. | -- | shxiyuanbio@163.com | CHINA | 6921 | 58 |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | -- | info@zzsrm.com | CHINA | 6846 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | -- | shzeysw@163.com | CHINA | 6550 | 58 |
| Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6039 | 58 |
| Riedel-de Haen AG | -- | United States | 6825 | 87 |