Y 134
- CAS No.
- 849662-80-2
- Chemical Name:
- Y 134
- Synonyms
- Y 134;Y-134,Y134;[6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE;Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[4-(1-methylethyl)-1-piperazinyl]phenyl]-
- CBNumber:
- CB82453417
- Molecular Formula:
- C28H28N2O3S
- Molecular Weight:
- 472.6
- MDL Number:
- MFCD09970973
- MOL File:
- 849662-80-2.mol
Last updated:2023-09-04 15:51:00
Y 134 price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 2676 | Y134 ≥98%(HPLC) | 849662-80-2 | 10 | $191 | 2021-12-16 | Buy |
Tocris | 2676 | Y134 ≥98%(HPLC) | 849662-80-2 | 50 | $751 | 2021-12-16 | Buy |
TRC | Y120005 | Y134 | 849662-80-2 | 100mg | $1260 | 2021-12-16 | Buy |
TRC | Y120005 | Y134 | 849662-80-2 | 10mg | $160 | 2021-12-16 | Buy |
TRC | Y120005 | Y134 | 849662-80-2 | 50mg | $710 | 2021-12-16 | Buy |
Y 134 Chemical Properties,Uses,Production
Uses
Y 134 is a SERM displaying selectivity for ERα over ERβ.
Definition
ChEBI: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-yl-1-piperazinyl)phenyl]methanone is an aromatic ketone.
Biological Activity
Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.
storage
Desiccate at RT
Y 134 Preparation Products And Raw materials
Raw materials
Preparation Products
Y 134 Suppliers
Global( 24)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9909 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3726 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
849662-80-2(Y 134)Related Search:
Y 134
[6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE
Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[4-(1-methylethyl)-1-piperazinyl]phenyl]-
Y-134,Y134
849662-80-2