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6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Structure
6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine structure
CAS No.
Chemical Name:
6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine
Synonyms
Ro 106-9920-d5;6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine
CBNumber:
CB82623274
Molecular Formula:
C10H2D5N5OS
Molecular Weight:
250.29128889
MDL Number:
MOL File:
Mol file
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6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC R637502 Ro106-9920-d5 10mg $1320 2021-12-16 Buy
Medical Isotopes, Inc. D52957 Ro106-9920-d5 1mg $650 2021-12-16 Buy
Product number Packaging Price Buy
R637502 10mg $1320 Buy
D52957 1mg $650 Buy

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Chemical Properties,Uses,Production

Uses

Labelled Ro 106-9920 (R637500). Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Preparation Products And Raw materials

Raw materials

Preparation Products

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Supplier Advantage
Chemsky (shanghai) International Co.,Ltd 60
6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Ro 106-9920-d5