5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
- CAS No.
- 720720-96-7
- Chemical Name:
- 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
- Synonyms
- 4,5,6,7-tetrahydro-5-Methyl-Thiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride;SWF-2;5-Methyl-4;Edoxaban-2;Edoxaban iMpurities 2;Yidu Saban Impurity B;Edoxaban Impurity 4 HCl;Edoxaban Impurity 32 HCl;Edoxaban Impurity B(HCl);Edoxaban Impurity 21 HCl
- CBNumber:
- CB82655282
- Molecular Formula:
- C8H11ClN2O2S
- Molecular Weight:
- 234.7
- MDL Number:
- MFCD25542379
- MOL File:
- 720720-96-7.mol
- MSDS File:
- SDS
Melting point | 199.0 to 203.0 °C |
---|---|
Boiling point | 175℃[at 101 325 Pa] |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly) |
form | Solid |
color | Pale Beige to Light Brown |
Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H335-H315-H319 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
HS Code | 2934.10.2000 |
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | M2819 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride >97.0%(HPLC) | 720720-96-7 | 200mg | $25 | 2024-03-01 | Buy |
TCI Chemical | M2819 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride >97.0%(HPLC) | 720720-96-7 | 1g | $74 | 2024-03-01 | Buy |
TRC | M330085 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride | 720720-96-7 | 25g | $820 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 66235 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylicAcidHCl | 720720-96-7 | 5G | $675 | 2021-12-16 | Buy |
ChemScene | CS-M3401 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride | 720720-96-7 | 5g | $58 | 2021-12-16 | Buy |
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Chemical Properties,Uses,Production
Uses
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).
Preparation
2-cyano-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride monohydrate (500.61 mg), ethanol (5 mL), and 4N aqueous lithium hydroxide (1.34 mL) were mixed at room temperature, and the resultant mixture was stirred at 50 °C for 7 hours. Until the reaction mixture was cooled with ice-water, 1N HCl in ethanol (7.5 mL) was added to the mixture. It was stirred for 1.5 hours. The precipitated crystals were collected by filtration, and were washed with ethanol (2 mL). The wet crystal was dried at room temperature under reduced pressure to obtain 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride.
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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zhuhai Hairuide Bioscience and Technology Co., Ltd | +8618928027945 | sales3@zhhairuide.com | China | 97 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 801 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10312 | 58 |
View Lastest Price from 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-23 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
720720-96-7
|
US $5.00 / kg | 1kg | ≥99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
![]() |
2023-09-08 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
720720-96-7
|
US $30.00 / kg | 1kg | 99% | 20 tons | Anhui Ruihan Technology Co., Ltd | |
![]() |
2023-09-08 | 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
720720-96-7
|
US $30.00 / kg | 1kg | 99% | 20 tons | Anhui Ruihan Technology Co., Ltd |
-
- 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
720720-96-7
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
720720-96-7
- US $30.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd
-
- 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
720720-96-7
- US $30.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd
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