Edoxaban-d6
- CAS No.
- 1304701-57-2
- Chemical Name:
- Edoxaban-d6
- Synonyms
- Edoxaban-d6;[2H6]-Edoxaban;Edoxaban hydrochloride salt;2H6]-Edoxaban hydrochloride salt;N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
- CBNumber:
- CB63163409
- Molecular Formula:
- C24H30ClN7O4S
- Molecular Weight:
- 548.06
- MDL Number:
- MFCD32661438
- MOL File:
- 1304701-57-2.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H315-H319 | |||||||||
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P501 | |||||||||
NFPA 704 |
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Edoxaban-d6 price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 25760 | Edoxaban-d6 ≥99% deuterated forms (d1-d6) | 1304701-57-2 | 500μg | $396 | 2024-03-01 | Buy |
Cayman Chemical | 25760 | Edoxaban-d6 ≥99% deuterated forms (d1-d6) | 1304701-57-2 | 1mg | $711 | 2024-03-01 | Buy |
Usbiological | 448076 | Edoxaban-d6 | 1304701-57-2 | 500ug | $531 | 2021-12-16 | Buy |
TRC | E555522 | Edoxaban-d6 | 1304701-57-2 | 5mg | $1850 | 2021-12-16 | Buy |
AK Scientific | 4287DK | N-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide | 1304701-57-2 | 1mg | $889 | 2021-12-16 | Buy |
Edoxaban-d6 Chemical Properties,Uses,Production
Description
Edoxaban-d6 is intended for use as an internal standard for the quantification of edoxaban by GC- or LC-MS. Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma. Oral administration of edoxaban (0.5-12.5 mg/kg) reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis. It also reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis. Formulations containing edoxaban have been used to prevent stroke in patients with atrial fibrillation.
Uses
Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.
Edoxaban-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
Edoxaban-d6 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 7177 | 65 |
Clearsynth Canada Inc. | +1.415.685.4395 | enquiry@clearsynth.com | Canada | 912 | 58 |
Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 | amber@biochempartner.com | China | 3063 | 58 |
Shenzhen Popeye Biotechnology Co. Ltd. | 0755-86320212 | popeye02@qq.com | China | 310 | 58 |
Jinan blalong chemical co. LTD | 2710913286@.com | 1513643261@qq.com | China | 14253 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Shenzhen ruikai de biotechnology co., ltd. | 0755-61348847 17820674378 | 2682116078@qq.com | China | 7844 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Manhag Testing Technology Co., Ltd | 020-020-3846236 17688849268 | 2443244976@qq.com | China | 7775 | 58 |
Cato Research Chemicals Inc. | 020-81960175-877 18933936954 | tianwen.zhan@cato-chem.com | China | 7728 | 58 |
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