Edoxaban-d6
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- $396 - $1850
- Product name: Edoxaban-d6
- CAS: 1304701-57-2
- MF: C24H30ClN7O4S
- MW: 548.06
- EINECS:
- MDL Number:MFCD32661438
- Synonyms:Edoxaban-d6;N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide;[2H6]-Edoxaban;Edoxaban hydrochloride salt;2H6]-Edoxaban hydrochloride salt
6 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- Cayman Chemical
- TRC
- Usbiological
Package
- 500ug
- 500μg
- 1mg
- 5mg
- Manufactureraablocks
- Product numberAA01E0QG
- Product descriptionEdoxaban-d6 ≥99%deuteratedforms(d1-d6)
- Packaging1mg
- Price$782
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4287DK
- Product descriptionN-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
- Packaging1mg
- Price$889
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25760
- Product descriptionEdoxaban-d6 ≥99% deuterated forms (d1-d6)
- Packaging500μg
- Price$396
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25760
- Product descriptionEdoxaban-d6 ≥99% deuterated forms (d1-d6)
- Packaging1mg
- Price$711
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberE555522
- Product descriptionEdoxaban-d6
- Packaging5mg
- Price$1850
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number448076
- Product descriptionEdoxaban-d6
- Packaging500ug
- Price$531
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
aablocks | AA01E0QG | Edoxaban-d6 ≥99%deuteratedforms(d1-d6) | 1mg | $782 | 2021-12-16 | Buy |
AK Scientific | 4287DK | N-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide | 1mg | $889 | 2021-12-16 | Buy |
Cayman Chemical | 25760 | Edoxaban-d6 ≥99% deuterated forms (d1-d6) | 500μg | $396 | 2024-03-01 | Buy |
Cayman Chemical | 25760 | Edoxaban-d6 ≥99% deuterated forms (d1-d6) | 1mg | $711 | 2024-03-01 | Buy |
TRC | E555522 | Edoxaban-d6 | 5mg | $1850 | 2021-12-16 | Buy |
Usbiological | 448076 | Edoxaban-d6 | 500ug | $531 | 2021-12-16 | Buy |
Properties
Melting point :>205°C (dec.)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), Dichloromethane (Slightly)
form :Solid
color :Pale Orange to Pale Red
Stability :Hygroscopic
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), Dichloromethane (Slightly)
form :Solid
color :Pale Orange to Pale Red
Stability :Hygroscopic
Safety Information
Symbol(GHS): |
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Description
Edoxaban-d6 is intended for use as an internal standard for the quantification of edoxaban by GC- or LC-MS. Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma. Oral administration of edoxaban (0.5-12.5 mg/kg) reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis. It also reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis. Formulations containing edoxaban have been used to prevent stroke in patients with atrial fibrillation.More related product prices
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