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KRN383
- CAS No.
- 919767-02-5
- Chemical Name:
- KRN383
- Synonyms
- KRN383;Urea, N-[4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]-1,5-cyclohexadien-1-yl]-
- CBNumber:
- CB82731085
- Molecular Formula:
- C17H17N3O4
- Molecular Weight:
- 327.33
- MDL Number:
- MFCD28138417
- MOL File:
- 919767-02-5.mol
Last updated:2023-03-31 09:12:57
KRN383 Chemical Properties,Uses,Production
Description
KRN383 also inhibited the proliferation of the ITD-positive cell lines with IC(50) values of < or =2.9 nM. A single oral administration of 80 mg/kg of KRN383 eradicated ITD-positive xenograft tumors in nude mice and prolonged the survival of SCID mice carrying ITD-positive AML cells. The effectiveness of a single oral dose of KRN383 suggests that it has the potential to be used in a wide variety of clinical regimens, including multicycle and combination therapies.
KRN383 Preparation Products And Raw materials
Raw materials
Preparation Products
KRN383 Suppliers
Global( 1)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28118 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
KRN383
Urea, N-[4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]-1,5-cyclohexadien-1-yl]-
919767-02-5