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ChemicalBook >> CAS DataBase List >>2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Structure
2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol structure
CAS No.
304684-77-3
Chemical Name:
2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
Synonyms
Exo2;Exo2 >=98% (HPLC);2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol;Benzaldehyde, 4-hydroxy-3-methoxy-, 2-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)hydrazone
CBNumber:
CB82750352
Molecular Formula:
C18H18N4O2S
Molecular Weight:
354.43
MDL Number:
MFCD00380179
MOL File:
304684-77-3.mol
Last updated:2023-05-04 17:34:37
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2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Properties

Boiling point 591.0±50.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form powder
pka 8.79±0.35(Predicted)
color yellow
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

SAFETY

Risk and Safety Statements

WGK Germany  3

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E7159 Exo2 ≥98% (HPLC) 304684-77-3 5mg $108 2024-03-01 Buy
Sigma-Aldrich E7159 Exo2 ≥98% (HPLC) 304684-77-3 25mg $335 2024-03-01 Buy
Biorbyt Ltd orb545927 Exo2 >98% 304684-77-3 25mg $469.2 2021-12-16 Buy
American Custom Chemicals Corporation PRB0000014 EXO2 95.00% 304684-77-3 5MG $649.35 2021-12-16 Buy
American Custom Chemicals Corporation PRB0000014 EXO2 95.00% 304684-77-3 25MG $842.26 2021-12-16 Buy
Product number Packaging Price Buy
E7159 5mg $108 Buy
E7159 25mg $335 Buy
orb545927 25mg $469.2 Buy
PRB0000014 5MG $649.35 Buy
PRB0000014 25MG $842.26 Buy

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Chemical Properties,Uses,Production

Description

Exo2 (304684-77-3) disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells.1 May be used to completely ablate the Golgi apparatus.1 Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce tubulation and merging of the TGN and endosomal compartments.2? It perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network, in contrast to cholera toxin.1,2 Accelerates degradation of perilipin-2 proteins.3

Definition

ChEBI: Exo2 is a member of phenols and a member of methoxybenzenes.

References

1) Feng et al. (2004), Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells; EMBO Rep., 5 596 2) Spooner et al. (2008), The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network; Biochem. J., 414 471 3) Pauloin et al. (2016), The perilipin-2 (adipophilin) coat of cytosolic lipid droplets is regulated by an Arf1-dependent mechanism in the HC11 mouse mammary epithelial cells; Cell Biol. Int., 40 143

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 780229652@qq.com China 1144 58
Supplier Advantage
Energy Chemical 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shaoguan Qicheng Biotechnology Co., Ltd 58

304684-77-3(2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol)Related Search:

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2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol Exo2 Exo2 >=98% (HPLC) Benzaldehyde, 4-hydroxy-3-methoxy-, 2-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)hydrazone 304684-77-3