ChemicalBook >> CAS DataBase List >>3,4-Methylenedioxy-beta-nitrostyrene
3,4-Methylenedioxy-beta-nitrostyrene
- CAS No.
- 1485-00-3
- Chemical Name:
- 3,4-Methylenedioxy-beta-nitrostyrene
- Synonyms
- MDBN;MNS (MDBN);NSC 170724;5-(2-Nitrovinyl);AKOS BBS-00006781;Syk Inhibitor III;TIMTEC-BB SBB007833;-nitrostyrene, MDBN);MNS (NSC 170724, MDBN);5-nitrovinyl-3-benzodioxole
- CBNumber:
- CB8314918
- Molecular Formula:
- C9H7NO4
- Molecular Weight:
- 193.16
- MDL Number:
- MFCD00014575
- MOL File:
- 1485-00-3.mol
Last updated:2024-11-18 17:01:59
| Melting point | 159-163 °C |
|---|---|
| Boiling point | 329.36°C (rough estimate) |
| Density | 1.4058 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Soluble in DMSO (up to 50 mg/ml). |
| form | Yellow to brown solid |
| color | Yellow |
| Sensitive | Light Sensitive |
| BRN | 192350 |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| InChI | InChI=1S/C9H7NO4/c11-10(12)4-3-7-1-2-8-9(5-7)14-6-13-8/h1-5H,6H2 |
| InChIKey | KFLWBZPSJQPRDD-UHFFFAOYSA-N |
| SMILES | O1C2=CC=C(C=C[N+]([O-])=O)C=C2OC1 |
| CAS DataBase Reference | 1485-00-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | 3,4-Methylenedioxy-«beta»-nitrostyrene(1485-00-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| Hazard Codes | Xn,Xi,T | |||||||||
| Risk Statements | 36/37/38-22-25 | |||||||||
| Safety Statements | 36/37/39-26-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| RTECS | WL5270000 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
3,4-Methylenedioxy-beta-nitrostyrene price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S352918 | 3,4-METHYLENEDIOXY-BETA-NITROSTYRENE Aldrich | 1485-00-3 | 250mg | $179 | 2024-03-01 | Buy |
| Sigma-Aldrich | 574713 | Syk Inhibitor III | 1485-00-3 | 50mg | $172 | 2024-03-01 | Buy |
| Alfa Aesar | L09139 | 3,4-Methylenedioxy-beta-nitrostyrene, 98% | 1485-00-3 | 10g | $65.7 | 2021-12-16 | Buy |
| Alfa Aesar | L09139 | 3,4-Methylenedioxy-beta-nitrostyrene, 98% | 1485-00-3 | 50g | $251 | 2021-12-16 | Buy |
| Cayman Chemical | 15206 | MNS ≥95% | 1485-00-3 | 10mg | $48 | 2024-03-01 | Buy |
3,4-Methylenedioxy-beta-nitrostyrene Chemical Properties,Uses,Production
Description
MDBN (1485-00-3) is an irreversible inhibitor of p97 (IC50 < 10 μM). Cell permeable.
Chemical Properties
yellow powder
Uses
MDBN is a Src and Syk kinase inhibitor that prevents phosphorylation and cytoskeletal association of GPIIb/IIIa and talin.
Biological Activity
Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC 50 = 12.7 μ M for thrombin-induced platelet aggregation). Exhibits no effects on Ca 2+ -dependent enzymes, PKC or arachidonic acid metabolism.
References
1) Chou et al. (2011), Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system; J. Biol. Chem., 286 16546
3,4-Methylenedioxy-beta-nitrostyrene Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 135)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| ENBRIDGE PHARMTECH CO., LTD. | +8613812269233 | tinayang@enbridgepharm.com | China | 322 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13505 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
View Lastest Price from 3,4-Methylenedioxy-beta-nitrostyrene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-18 | MNS
1485-00-3
|
US $45.00-72.00 / mg | 98.45% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-10-25 | 3,4-Methylenedioxy-beta-nitrostyrene
1485-00-3
|
US $50.00 / kg | 1kg | 0.99 | 10000 | Hebei Yanxi Chemical Co., Ltd. | |
 |
2024-07-06 | 3,4-Methylenedioxy-beta-nitrostyrene
1485-00-3
|
US $0.00 / kg | 1kg | 0.99 | 10T | Shandong Hanjiang Chemical Co., Ltd |
-
- MNS
1485-00-3
- US $45.00-72.00 / mg
- 98.45%
- TargetMol Chemicals Inc.
-
- 3,4-Methylenedioxy-beta-nitrostyrene
1485-00-3
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- 3,4-Methylenedioxy-beta-nitrostyrene
1485-00-3
- US $0.00 / kg
- 0.99
- Shandong Hanjiang Chemical Co., Ltd
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Syk Inhibitor III - CAS 1485-00-3 - Calbiochem
4-Methylenedioxy-beta-nitrostyrene
thrombin,aggregation,NSC170724,Inhibitor,Src,MNS,NSC 170724,activation,inhibit,NSC-170724,Spleen tyrosine kinase,derivative,GPIIb/IIIa,beta-nitrostyrene,Syk,platelet
MNS (3，4-Methylenedioxy-β-nitrostyrene， MDBN)
1485-00-3
Kinase/Phosphatase Biology
Non-Receptor Tyrosine Kinase Inhibitors
Spleen Tyrosine Kinase (Syk)
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Ethanes/ethenes
Inhibitors