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6(S)-Lipoxin A4

6(S)-Lipoxin A4 Structure
6(S)-Lipoxin A4 structure
CAS No.
94292-80-5
Chemical Name:
6(S)-Lipoxin A4
Synonyms
6(S)-Lipoxin A4;IXAQOQZEOGMIQS-UZDWIPAXSA-N;7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, (5S,6S,7E,9E,11Z,13E,15S)-
CBNumber:
CB83152519
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MDL Number:
MOL File:
94292-80-5.mol
Last updated:2023-05-21 10:59:17
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6(S)-Lipoxin A4 Properties

storage temp. Store at -20°C
solubility DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

6(S)-Lipoxin A4 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10049 6(S)-Lipoxin A4 ≥95% 94292-80-5 25μg $274 2024-03-01 Buy
Cayman Chemical 10049 6(S)-Lipoxin A4 ≥95% 94292-80-5 50μg $519 2024-03-01 Buy
Cayman Chemical 10049 6(S)-Lipoxin A4 ≥95% 94292-80-5 100μg $980 2024-03-01 Buy
Product number Packaging Price Buy
10049 25μg $274 Buy
10049 50μg $519 Buy
10049 100μg $980 Buy

6(S)-Lipoxin A4 Chemical Properties,Uses,Production

Description

The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to be an artifact by these authors because it lacked the potency of the 5(S),6(R) isomer with respect to contraction of isolated guinea pig lung parenchymal strips. It has not been possible to isolate “natural” LXA4 from humans or other mammals in amounts sufficient for determination of absolute stereochemistry. Most authors refer to LXA4 as the 5(S),6(R), 11-cis isomer, but it is not clear that biological systems are aware of or agree with these conventions. Historically, conjugated tetraenes flanked by hydroxyl groups of mixed stereochemistry have been marketed as ''Lipoxin A4'' by some biomolecular supply companies. The availability of single pure LXA4 enantiomers should help to reduce the confusion this has caused.

Definition

ChEBI: 6-epi-lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6S)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. It has a role as a metabolite. It is a lipoxin, a long-chain fatty acid and a hydroxy polyunsaturated fatty acid.

6(S)-Lipoxin A4 Preparation Products And Raw materials

Raw materials

(E)-2-Penten-4-yn-1-ol

Preparation Products

6(S)-Lipoxin A4 Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
6(S)-Lipoxin A4 IXAQOQZEOGMIQS-UZDWIPAXSA-N 7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, (5S,6S,7E,9E,11Z,13E,15S)- 94292-80-5