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CeMMEC1

CeMMEC1 structure

CAS No.: 440662-09-9

Chemical Name:: CeMMEC1

Synonyms: CeMMEC1;cemmecl;CeMMEC1(free base);Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1;4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-

CBNumber:: CB83171705

Molecular Formula:: C19H16N2O4

Molecular Weight:: 336.34

MDL Number:: MFCD02939849

MOL File:: 440662-09-9.mol

Last updated:2024-07-02 08:55:27

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CeMMEC1 Properties

Boiling point	590.1±50.0 °C(Predicted)
Density	1.386±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form	A crystalline solid
pka	11.38±0.20(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

NFPA 704

	0
2		0

CeMMEC1 price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	19956	CeMMEC1 ≥98%	440662-09-9	500μg	$32	2024-03-01	Buy
Cayman Chemical	19956	CeMMEC1 ≥98%	440662-09-9	1mg	$61	2024-03-01	Buy
Cayman Chemical	19956	CeMMEC1 ≥98%	440662-09-9	5mg	$243	2024-03-01	Buy
Cayman Chemical	19956	CeMMEC1 ≥98%	440662-09-9	10mg	$426	2024-03-01	Buy
TRC	C256565	CeMMEC1	440662-09-9	5mg	$310	2021-12-16	Buy

Product number	Packaging	Price	Buy
19956	500μg	$32	Buy
19956	1mg	$61	Buy
19956	5mg	$243	Buy
19956	10mg	$426	Buy
C256565	5mg	$310	Buy

CeMMEC1 Chemical Properties,Uses,Production

Description

CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (K_d = 1.8 μM; IC₅₀ = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.

Uses

CeMMEC1, shows high affinity for TAF1, and is an inhibitor of BRD4.

storage

Store at -20°C

CeMMEC1 Preparation Products And Raw materials

Raw materials

Preparation Products

CeMMEC1 Suppliers

Global( 49)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29826	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9664	60
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4663	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
InvivoChem	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Amadis Chemical Company Limited	58
Spectrum Chemical Manufacturing Corp.	60
Dalian Meilun Biotech Co., Ltd.	58

View Lastest Price from CeMMEC1 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-10	CeMMEC1 440662-09-9	US $0.01 / KG	1KG	98%; 99%	500g;1kg； 25kg	Career Henan Chemical Co

CeMMEC1
440662-09-9
US $0.01 / KG
98%; 99%
Career Henan Chemical Co

CeMMEC1 Spectrum

CeMMEC1(440662-09-9)¹HNMR

CeMMEC1 4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo- CeMMEC1(free base) cemmecl Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1 440662-09-9