4-Hydroxy-3,5-dimethoxycinnamic acid
- CAS No.
- 530-59-6
- Chemical Name:
- 4-Hydroxy-3,5-dimethoxycinnamic acid
- Synonyms
- SINAPIC ACID;SINAPINIC ACID;3,5-DIMETHOXY-4-HYDROXYCINNAMIC ACID;(E)-3-(4-hydroxy-3,5-diMethoxyphenyl)acrylic acid;NSC 59261;Dimethoxy MS;Synapoic acid;Synapitic Acid;SIMPLEXOLIN(RG);rans-sinapicaci
- CBNumber:
- CB8328696
- Molecular Formula:
- C11H12O5
- Molecular Weight:
- 224.21
- MDL Number:
- MFCD00004401
- MOL File:
- 530-59-6.mol
- MSDS File:
- SDS
Melting point | ~202 °C |
---|---|
Boiling point | 285.61°C (rough estimate) |
Density | 1.1478 (rough estimate) |
refractive index | 1.4720 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | H2O: slightly soluble |
form | powder |
pka | 4.53±0.10(Predicted) |
color | white |
Odor | at 100.00?%. odorless |
Water Solubility | insoluble |
BRN | 2130006 |
Stability | Stable. Incompatible with strong oxidizing agents, strong bases. Combustible. |
LogP | 0.997 (est) |
CAS DataBase Reference | 530-59-6(CAS DataBase Reference) |
FDA UNII | 68A28V6010 |
NIST Chemistry Reference | Cinnamic acid, 4-hydroxy-3,5-dimethoxy-(530-59-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29189900 | |||||||||
NFPA 704 |
|
4-Hydroxy-3,5-dimethoxycinnamic acid price More Price(57)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 85429 | Sinapic acid matrix substance for MALDI-MS, ≥99.0% (T) | 530-59-6 | 1g | $91 | 2024-03-01 | Buy |
Sigma-Aldrich | 49508 | Sinapic acid matrix substance for MALDI-MS, ≥99.5%, Ultra pure | 530-59-6 | 10x10mg | $332 | 2024-03-01 | Buy |
TCI Chemical | D1765 | 3,5-Dimethoxy-4-hydroxycinnamic Acid >98.0%(GC)(T) | 530-59-6 | 5g | $57 | 2024-03-01 | Buy |
TCI Chemical | D1765 | 3,5-Dimethoxy-4-hydroxycinnamic Acid >98.0%(GC)(T) | 530-59-6 | 25g | $166 | 2024-03-01 | Buy |
Alfa Aesar | A15676 | 4-Hydroxy-3,5-dimethoxycinnamic acid, 98% | 530-59-6 | 1g | $30.65 | 2024-03-01 | Buy |
4-Hydroxy-3,5-dimethoxycinnamic acid Chemical Properties,Uses,Production
Chemical Properties
yellow-brown crystalline powder
Uses
Sinapic acid was suitable as phenolic standard for HPLC analysis in determination of Sinapic acid derivatives in Canola extracts. 10 g/L of sinapinic acid with solvent was suitable as matrix for ultraviolet laser desorption mass spectrometric determination of proteins. It was also suitable to use as matrix for MALDI-TOFMS and MALDI-ion mobility-TOFMS to determine phospholipids in tissue.
Uses
4-Hydroxy-3,5-dimethoxycinnamic acid is a commonly used matrix in MALDI mass spectrometry. It is a useful matrix for a wide variety of peptides and proteins. It serves well as a matrix for MALDI due to its ability to absorb laser radiation and to also donate protons (H+) to the analyte of interest.
Definition
ChEBI: A monohydroxycinnamic acid that is cinnamic acid in which the phenyl hydrogens at positions 3, 4, and 5 are replaced by methoxy, hydroxy, and methoxy groups, respectively.
General Description
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
Biochem/physiol Actions
On removal of amino group from phenylalanine, catalysing with enzyme phenylalanine ammonia-lyase forms cinnamic acid. The precursor of hydroxycinnamates is produced after hydroxylation of benzene ring. One of the precursors produced is sinapic acid. Sinapic acid exhibits antimicrobial, antioxidant, anticancer, anti-inflammatory, and anti-anxiety activity. Sinapine (sinapoyl choline) has been acknowledged as an acetylcholinesterase inhibitor, making it therapeutically applicable in treatment of various diseases. 4-Vinylsyringol (a decarboxylation product of sinapic acid) is a potent antimutagenic and antioxidative agent, involved in suppressing the induction of inflammatory cytokines and carcinogenesis. Owing to their anti-oxidative activity, these compounds have been considered to be potentially employed in the pharmaceutical industry, cosmetics and food processing.
Purification Methods
Crystallise it from water. [Beilstein 10 H 508, 10 IV 2104.]
4-Hydroxy-3,5-dimethoxycinnamic acid Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3777 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from 4-Hydroxy-3,5-dimethoxycinnamic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
|
2023-02-24 | Sinapic acid
530-59-6
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
![]() |
2023-02-13 | Sinapinic acid
530-59-6
|
US $10.00 / KG | 1KG | 99% | 50MT | Hebei baicao biology science and technology co., ltd | |
![]() |
2019-07-06 | 4-Hydroxy-3,5-dimethoxycinnamic acid
530-59-6
|
US $1.00 / KG | 1KG | 98% | 1kg,5kg,100kg | Career Henan Chemical Co |
-
- Sinapic acid
530-59-6
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Sinapinic acid
530-59-6
- US $10.00 / KG
- 99%
- Hebei baicao biology science and technology co., ltd
-
- 4-Hydroxy-3,5-dimethoxycinnamic acid
530-59-6
- US $1.00 / KG
- 98%
- Career Henan Chemical Co