4-Hydroxy-3,5-dimethoxycinnamic acid
- CAS No.
- 530-59-6
- Chemical Name:
- 4-Hydroxy-3,5-dimethoxycinnamic acid
- Synonyms
- SINAPIC ACID;SINAPINIC ACID;3,5-DIMETHOXY-4-HYDROXYCINNAMIC ACID;(E)-3-(4-hydroxy-3,5-diMethoxyphenyl)acrylic acid;NSC 59261;Dimethoxy MS;Synapoic acid;Synapitic Acid;SIMPLEXOLIN(RG);rans-sinapicaci
- CBNumber:
- CB8328696
- Molecular Formula:
- C11H12O5
- Molecular Weight:
- 224.21
- MDL Number:
- MFCD00004401
- MOL File:
- 530-59-6.mol
- MSDS File:
- SDS
| Melting point | ~202 °C |
|---|---|
| Boiling point | 285.61°C (rough estimate) |
| Density | 1.1478 (rough estimate) |
| refractive index | 1.4720 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: slightly soluble |
| form | powder |
| pka | 4.53±0.10(Predicted) |
| color | white |
| Odor | at 100.00?%. odorless |
| Water Solubility | insoluble |
| BRN | 2130006 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong bases. Combustible. |
| LogP | 0.997 (est) |
| CAS DataBase Reference | 530-59-6(CAS DataBase Reference) |
| FDA UNII | 68A28V6010 |
| NIST Chemistry Reference | Cinnamic acid, 4-hydroxy-3,5-dimethoxy-(530-59-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
4-Hydroxy-3,5-dimethoxycinnamic acid price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 85429 | Sinapic acid matrix substance for MALDI-MS, ≥99.0% (T) | 530-59-6 | 1g | $91 | 2024-03-01 | Buy |
| Sigma-Aldrich | 49508 | Sinapic acid matrix substance for MALDI-MS, ≥99.5%, Ultra pure | 530-59-6 | 10x10mg | $332 | 2024-03-01 | Buy |
| TCI Chemical | D1765 | 3,5-Dimethoxy-4-hydroxycinnamic Acid >98.0%(GC)(T) | 530-59-6 | 5g | $57 | 2024-03-01 | Buy |
| TCI Chemical | D1765 | 3,5-Dimethoxy-4-hydroxycinnamic Acid >98.0%(GC)(T) | 530-59-6 | 25g | $166 | 2024-03-01 | Buy |
| Alfa Aesar | A15676 | 4-Hydroxy-3,5-dimethoxycinnamic acid, 98% | 530-59-6 | 1g | $30.65 | 2024-03-01 | Buy |
4-Hydroxy-3,5-dimethoxycinnamic acid Chemical Properties,Uses,Production
Chemical Properties
yellow-brown crystalline powder
Uses
Sinapic acid was suitable as phenolic standard for HPLC analysis in determination of Sinapic acid derivatives in Canola extracts. 10 g/L of sinapinic acid with solvent was suitable as matrix for ultraviolet laser desorption mass spectrometric determination of proteins. It was also suitable to use as matrix for MALDI-TOFMS and MALDI-ion mobility-TOFMS to determine phospholipids in tissue.
Uses
4-Hydroxy-3,5-dimethoxycinnamic acid is a commonly used matrix in MALDI mass spectrometry. It is a useful matrix for a wide variety of peptides and proteins. It serves well as a matrix for MALDI due to its ability to absorb laser radiation and to also donate protons (H+) to the analyte of interest.
Definition
ChEBI: A monohydroxycinnamic acid that is cinnamic acid in which the phenyl hydrogens at positions 3, 4, and 5 are replaced by methoxy, hydroxy, and methoxy groups, respectively.
General Description
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
Biochem/physiol Actions
On removal of amino group from phenylalanine, catalysing with enzyme phenylalanine ammonia-lyase forms cinnamic acid. The precursor of hydroxycinnamates is produced after hydroxylation of benzene ring. One of the precursors produced is sinapic acid. Sinapic acid exhibits antimicrobial, antioxidant, anticancer, anti-inflammatory, and anti-anxiety activity. Sinapine (sinapoyl choline) has been acknowledged as an acetylcholinesterase inhibitor, making it therapeutically applicable in treatment of various diseases. 4-Vinylsyringol (a decarboxylation product of sinapic acid) is a potent antimutagenic and antioxidative agent, involved in suppressing the induction of inflammatory cytokines and carcinogenesis. Owing to their anti-oxidative activity, these compounds have been considered to be potentially employed in the pharmaceutical industry, cosmetics and food processing.
Purification Methods
Crystallise it from water. [Beilstein 10 H 508, 10 IV 2104.]
4-Hydroxy-3,5-dimethoxycinnamic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2993 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from 4-Hydroxy-3,5-dimethoxycinnamic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-20 | Sinapicacid
530-59-6
|
US $0.00-0.00 / kg | 1kg | 98% | 5000kg | Wuhan Fortuna Chemical Co.,Ltd | |
 |
2023-02-24 | Sinapic acid
530-59-6
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2023-02-13 | Sinapinic acid
530-59-6
|
US $10.00 / KG | 1KG | 99% | 50MT | Hebei baicao biology science and technology co., ltd |
-
- Sinapicacid
530-59-6
- US $0.00-0.00 / kg
- 98%
- Wuhan Fortuna Chemical Co.,Ltd
-
- Sinapic acid
530-59-6
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Sinapinic acid
530-59-6
- US $10.00 / KG
- 99%
- Hebei baicao biology science and technology co., ltd