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(+)-Biotin-PEG8-NHS Ester

CAS No.
2143968-03-8
Chemical Name:
(+)-Biotin-PEG8-NHS Ester
Synonyms
Biotin-PEG8-SPA;(+)-Biotin-PEG8-NHS Ester;2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate;4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB83311639
Molecular Formula:
C33H56N4O14S
Molecular Weight:
764.88
MDL Number:
MFCD27977502
MOL File:
2143968-03-8.mol
Last updated:2023-02-23 14:24:01

(+)-Biotin-PEG8-NHS Ester Properties

Density 1.29±0.1 g/cm3(Predicted)
pka 13.90±0.40(Predicted)

(+)-Biotin-PEG8-NHS Ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
purepeg 246908 (+)-Biotin-PEG8-NHSEster min.95% 2143968-03-8 50mg $140 2021-12-16 Buy
Product number Packaging Price Buy
246908 50mg $140 Buy

(+)-Biotin-PEG8-NHS Ester Chemical Properties,Uses,Production

Biological Activity

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

(+)-Biotin-PEG8-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-Biotin-PEG8-NHS Ester Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9895 58
Borenpharm Co., Ltd 027-65563561 sales@borenpharm.com China 1245 55
Changzhou Hopschain Chemical Co.,Ltd. 0519-85528066 13775048983 sales@hopschem.com China 31553 55
Jinan elephant international trading co., LTD 13006575422@163.com China 6355 58
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9994 58

View Lastest Price from (+)-Biotin-PEG8-NHS Ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-PEG8-NHS ester pictures 2024-04-02 Biotin-PEG8-NHS ester
2143968-03-8
US $0.00 / mg 500mg >98.00% 500mg Xian confluore Biological Technology Co., Ltd.
(+)-Biotin-PEG8-NHS Ester Biotin-PEG8-SPA 4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester 2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate 2143968-03-8 SiChem peg Biotin