ChemicalBook >> CAS DataBase List >>ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate
ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate
- CAS No.
- 118988-04-8
- Chemical Name:
- ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate
- Synonyms
- HO-PEG3-CH2COOEt;Hydroxy-PEG3-ethyl acetate;ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate;Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester;HO-PEG3-CH2COOEt/Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester
- CBNumber:
- CB83367469
- Molecular Formula:
- C10H20O6
- Molecular Weight:
- 236.26
- MDL Number:
- MFCD25956292
- MOL File:
- 118988-04-8.mol
Last updated:2023-02-23 14:24:01
ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Chemical Properties,Uses,Production
Biological Activity
Hydroxy-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate Preparation Products And Raw materials
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HO-PEG3-CH2COOEt
ethyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate
Hydroxy-PEG3-ethyl acetate
HO-PEG3-CH2COOEt/Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester
Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, ethyl ester
118988-04-8