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C2 CERAMIDE

C2 CERAMIDE structure

CAS No.: 3102-57-6

Chemical Name:: C2 CERAMIDE

Synonyms: N-ACETYLSPHINGOSINE;N-ACETYL-D-SPHINGOSINE;N-ETHANOYL-D-ERYTHRO-SPHINGOSINE;CERAMIDE C2;C2 CERAMIDE;C2:0 CERAMIDE;TOC Ceramide;ACETYL CERAMIDE;C14 SPHINGOID BASE;N-Acetylsphigosine

CBNumber:: CB8342539

Molecular Formula:: C20H39NO3

Molecular Weight:: 341.53

MDL Number:: MFCD00153903

MOL File:: 3102-57-6.mol

MSDS File:: SDS

Last updated:2024-11-13 18:13:23

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C2 CERAMIDE Properties

Melting point	93-96 °C
Boiling point	477.13°C (rough estimate)
Density	1.0283 (rough estimate)
refractive index	1.5614 (estimate)
storage temp.	−20°C
solubility	DMSO: soluble
pka	13.50±0.20(Predicted)
form	powder
color	white
Stability	Moisture Sensitive
FDA UNII	8YTC7R47CW

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
HS Code	29241990

C2 CERAMIDE price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	01912	N-Acetyl-D-sphingosine ≥98.0% (TLC)	3102-57-6	50mg	$101.6	2024-03-01	Buy
Sigma-Aldrich	01912	N-Acetyl-D-sphingosine ≥98.0% (TLC)	3102-57-6	250mg	$342.8	2024-03-01	Buy
Alfa Aesar	J60534	N-Acetyl-D-sphingosine, 98%	3102-57-6	5mg	$112	2023-06-20	Buy
Alfa Aesar	J60534	N-Acetyl-D-sphingosine, 98%	3102-57-6	1mg	$20.5	2021-12-16	Buy
Cayman Chemical	62510	C-2 Ceramide ≥98%	3102-57-6	1mg	$21	2024-03-01	Buy

Product number	Packaging	Price	Buy
01912	50mg	$101.6	Buy
01912	250mg	$342.8	Buy
J60534	5mg	$112	Buy
J60534	1mg	$20.5	Buy
62510	1mg	$21	Buy

C2 CERAMIDE Chemical Properties,Uses,Production

Description

C2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides. These processes include differentiation of HL-60 cells, induction of apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. C2 ceramide also enhances the expression of COX-2 in human dermal fibroblasts and stimulates the growth of bovine aortic smooth muscle cells. The ability of C2 ceramide to destabilize membranes may be responsible for its inhibition of platelet aggregation.

Chemical Properties

White Crystalline Solid

Uses

A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2

Uses

Inhibits cell proliferation and induces monocytic differentiation of HL-60 cells. Activates protein phosphatases

Definition

ChEBI: N-acetylsphingosine is a N-acylsphingosine that has an acetamido group at position 2.

Biological Activity

A potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro .

Biochem/physiol Actions

Cell-permeable, biologically active ceramide. It induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases.

storage

Desiccate at -20°C

References

1) Minano et al. (2008), C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3; J. Neurosci. Res., 86 1734 2) Prinetti et al. (1997), Involvement of a ceramide activated protein phosphatase in the differentiation of neuroblastoma Neuro2a cells; FEBS Lett., 414 475 3) Zhang et al. (1997), Kinase suppressor of Ras is ceramide-activated protein kinase; Cell, 89 63 4) Matsuzaka et al. (2016) Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation] 5) Matsuzaka et al. (2016) Characterization and functional analysis of extracellular vesicles and muscle-abundant miRNA in C2C12 myocytes and Mdx mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation]

C2 CERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

C2 CERAMIDE Suppliers

Global( 120)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3958	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9639	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49978	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Shanghai Likang New Materials Co., Limited	+86-16631818819 +86-17736933208	3684455296@qq.com	China	9300	58
Shanghai Renshi Pharmatech Co., LTD	021-61150625 17721318029	info@renshipharma.com	China	116	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
LEAPCHEM CO., LTD.	58
Shanghai Likang New Materials Co., Limited	58
Shanghai Renshi Pharmatech Co., LTD	55
J & K SCIENTIFIC LTD.	76

View Lastest Price from C2 CERAMIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-13	C2 Ceramide 3102-57-6	US $97.00-233.00 / mg		99.59%	10g	TargetMol Chemicals Inc.
	2024-08-11	C2 CERAMIDE 3102-57-6	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd

C2 Ceramide
3102-57-6
US $97.00-233.00 / mg
99.59%
TargetMol Chemicals Inc.

C2 CERAMIDE
3102-57-6
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

C2 CERAMIDE Spectrum

C2 CERAMIDE(3102-57-6)¹HNMR

3102-57-6(C2 CERAMIDE)Related Search:

6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE C6 CERAMIDE GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE C2 CERAMIDE DISIALOGANGLIOSIDE GD1B 2NA

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LIGNOCERIC CERAMIDE,LIGNOCERIC CERAMIDE LYSO-LACTOSYL CERAMIDE,LYSO-LACTOSYL CERAMIDE GANGLIOTRIOSYL CERAMIDE,GANGLIOTRIOSYL CERAMIDE N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE,N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE D-ERYTHRO-SPHINGOSINE

N-LIGNOCEROYL-D-SPHINGOSINE 1-BENZOATE N-BUTANOYL-D-ERYTHRO-SPHINGOSINE N-ARACHIDOYL-D-ERYTHRO-SPHINGOSINE

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N-ACETYL-D-ERYTHRO-SPHINGOSINE N-ACETYLSPHINGOSINE, D-ERYTHRO C14 SPHINGOID BASE C2:0 CERAMIDE C2-D-ERYTHRO-CERAMIDE C2 CERAMIDE C2 CERAMIDE OF D-ERYTHRO-C14-SPHINGOSINE CERAMIDE C2 D-ERYTHRO-SPHINGOSINE, N-ACETYL- ACETYL CERAMIDE N-ETHANOYL-D-ERYTHRO-SPHINGOSINE SYNTHE TICAL 99+% N-Ethanoyl-D-erythro-sphingosine, synthetical (D-erythro-N-Acetylsphingosine) D-erythro-Sphingoshine, N-Acetyl- N-Ethanoyl-D-sphingosine TOC Ceramide Acetyl ceramide, C2 ceramide N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]acetaMide (2S,3R,4E)-2-(Acetylamino)-4-octadecene-1,3-diol C2 Ceramide (d18:1/2:0) Acetamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]- D-erythro-Sphingosine, N-Acetyl- - CAS 3102-57-6 - Calbiochem N-Acetylsphigosine N-ACETYLSPHINGOSINE N-ACETYL-D-SPHINGOSINE N-ETHANOYL-D-ERYTHRO-SPHINGOSINE C2 Ceramide,C-2 Ceramide 3102-57-6 3102-57-5 7344-2-7 3101-57-6 BioChemical Anti-Proliferative Agents Antitumor Agents Cancer Research Mixed Fatty Acids Activators Fatty Acid Derivatives & Lipids Glycerols Inhibitors Protein Kinase Inhibitors and Activators Lipid signaling