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Mog (35-55)

CAS No.
149635-73-4
Chemical Name:
Mog (35-55)
Synonyms
MOG (35-55);MEVGWYRSPFSRVVHLYRNGK;MK21;MOG (35-55) TFA;MOG (35-55), RAT;MOG (MOUSE, RAT);MOG (RAT, MOUSE, 35-55);MOG (35-55), MOUSE, RAT;MOG (35-55) (rat, Mouse);H-MEVGWYRSPFSRVVHLYRNGK-OH
CBNumber:
CB8355199
Molecular Formula:
C118H177N35O29S
Molecular Weight:
2581.95
MDL Number:
MFCD06796003
MOL File:
149635-73-4.mol
Last updated:2024-10-28 16:48:35

Mog (35-55) Properties

Density 1.48±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility ≥32.25 mg/mL in H2O; insoluble in EtOH; ≥86 mg/mL in DMSO
form solid
color White to off-white
Water Solubility Soluble to 0.50 mg/ml in water
Sequence H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-VAL-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH
InChIKey JMTCEFUSRHYJBF-LTFOILMJNA-N

Mog (35-55) price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 2568 MOG(35-55) 149635-73-4 1 $229 2021-12-16 Buy
ApexBio Technology A8306 MOG(35-55) 149635-73-4 5mg $294 2021-12-16 Buy
American Custom Chemicals Corporation PEP0003907 MOG (35-55)-MOUSE, RAT 95.00% 149635-73-4 1MG $733.72 2021-12-16 Buy
ApexBio Technology A8306 MOG(35-55) 149635-73-4 1mg $98 2021-12-16 Buy
Product number Packaging Price Buy
2568 1 $229 Buy
A8306 5mg $294 Buy
PEP0003907 1MG $733.72 Buy
A8306 1mg $98 Buy

Mog (35-55) Chemical Properties,Uses,Production

Description

MOG (35-55) or myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. MOG (35-55) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. MOG (35-55) induces strong T and B cell responses and is highly encephalitogenic. MOG (35-55) induces T cell-mediated multiple sclerosis in animal models. When co-administered with ITE, MOG (35-55) induces tolerogenic dendritic cells and suppresses disease development in mouse preclinical models of multiple sclerosis.

Uses

Mog (35-55) can be used as an antigen immunized C57BL/6J mice to induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice.

Biological Activity

mog (35-55) is a truncated peptide derived from the human myelin oligodendrocyte glycoprotein (mog). mog, a member of the immunoglobulin superfamily, is expressed wildly in the central nervous system. in mouse and rat models for human multiple sclerosis, mog is involved in inducing the experimental autoimmune encephalomyelitis. humoral auto-immunity to the myelin oligodendrocyte glycoprotein (mog) may be associated with the pathogenesis of multiple sclerosis (ms) [1].mog (35-55) is involved in inducing autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination [2]. in hla-dr2-transgenic mice, myelin oligodendrocyte glycoprotein-35-55 peptide induced severe chronic experimental autoimmune encephalomyelitis [3].mog35-55 was highly encephalitogenic and could induce strong t and b cell responses in rats [4]. in nod/lt mice (h-2g7) and c57bl/6 mice (h-2b), single injection of mog35-55 in cfa could induce ms-like disease [4].

storage

Store at -20°C

References

[1]. de march a k, de bouwerie m, kolopp-sarda m n, et al. anti-myelin oligodendrocyte glycoprotein b-cell responses in multiple sclerosis[j]. journal of neuroimmunology, 2003, 135(1): 117-125.
[2]. slavin a, ewing c, liu j, et al. induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein[j]. autoimmunity, 1998, 28(2): 109-120.
[3]. rich c, link j m, zamora a, et al. myelin oligodendrocyte glycoprotein‐35–55 peptide induces severe chronic experimental autoimmune encephalomyelitis in hla‐dr2‐transgenic mice[j]. european journal of immunology, 2004, 34(5): 1251-1261.
[4]. slavin a, ewing c, liu j, et al. induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein[j]. autoimmunity, 1998, 28(2): 109-120.

Mog (35-55) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 143)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5857 58
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533 Ethan@dornechem.com China 3097 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
Hebei Anlijie Biotechnology Co., Ltd
+8619031013551 ably@aljbio.com China 144 58
Shanghai Affida new material science and technology center
+undefined15081010295 admin@oudaxin.com China 114 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 970 58
Alpha Biopharmaceuticals Co., Ltd
+86-15542445688 sales@alphabiopharm.com China 992 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18751 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
GenicBio Limited
+86-21-37621270 service@genicbio.com CHINA 991 58

View Lastest Price from Mog (35-55) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mog (35-55) pictures 2024-12-18 Mog (35-55)
149635-73-4
US $1.00 / g 1g 99% 100kg Dorne Chemical Technology co. LTD
Mog (35-55) pictures 2024-12-17 Mog (35-55)
149635-73-4
US $50.00-200.00 / g 10g 98% 2000kg hebei hongtan Biotechnology Co., Ltd
Mog (35-55) pictures 2024-12-10 Mog (35-55)
149635-73-4
US $0.00-0.00 / Box 1Box 99 50000KG/month Shanghai Affida new material science and technology center
  • Mog (35-55) pictures
  • Mog (35-55)
    149635-73-4
  • US $1.00 / g
  • 99%
  • Dorne Chemical Technology co. LTD
  • Mog (35-55) pictures
  • Mog (35-55)
    149635-73-4
  • US $50.00-200.00 / g
  • 98%
  • hebei hongtan Biotechnology Co., Ltd
  • Mog (35-55) pictures
  • Mog (35-55)
    149635-73-4
  • US $0.00-0.00 / Box
  • 99
  • Shanghai Affida new material science and technology center
H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH (MOUSE, RAT) MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS H-MEVGWYRSPFSRVVHLYRNGK-OH MET-GLU-VAL-GLY-TRP-TYR-ARG-PRO-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS: MEVGWYRSPFSRVVHLYRNGK MOG (35-55) (rat, Mouse) MYELIN OLIGODENDROCYTE GLYCOPRTOTEIN PEPTIDE FRAGMENT (33-55) RAT, MOUSE, MOG Peptide (33-55) Rat, Mouse Myelin Oligodendrocyte Glycoprotien (35-55) rat MOG (35-55) Myelin Oligodendrocyte Glycoprotein (35-55) MOG(35-55)| Myelin Oligodendrocyte Glycoprotein Peptide: 35-55,rat,mouse MYELIN OLIGODENDROCYTE GLYCOPROTEIN PEPTIDE (35-55) (RAT, MOUSE) MYELIN OLIGODENDROCYTE GLYCOPROTEIN PEPTIDE FRAGMENT 35-55 RAT, MOUSE MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55) (MOUSE, RAT) MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55), RAT MYELIN OLIGODENDROCYTE PROTEIN (35-55) MOG (35-55), RAT MOG (MOUSE, RAT) MOG PEPTIDE (35-55) (RAT, MOUSE) MOG (RAT, MOUSE, 35-55) MOG (35-55), MOUSE, RAT MK21 Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat L-Lysine, L-methionyl-L-α-glutamyl-L-valylglycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-seryl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparaginylglycyl- H-MET-GLU-VAL-GLY-TRP-TYR-ARG-SER-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH USP/EP/BP MOG (35-55) TFA L-Lysine,L-methionyl-L-a-glutamyl-L-valylglycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-seryl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparaginylglycyl- MEVGWYRSPFSRVVHLYRNGK MOG (35-55) (2S)-6-amino-2-[[2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-ca Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) 149635-73-4 C118H177N35O29S peptide Various Peptides