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Methyl pyruvate

CAS No.
600-22-6
Chemical Name:
Methyl pyruvate
Synonyms
Propanoic acid, 2-oxo-, methyl ester;METHYL 2-OXOPROPANOATE;PAME;ksby;PYR ME;METHYL PYRUVATE;Methyl pyruyate;MethylPyruvate>Methylpyruvate,96%;Methyl acetoformate
CBNumber:
CB8405108
Molecular Formula:
C4H6O3
Molecular Weight:
102.09
MDL Number:
MFCD00008754
MOL File:
600-22-6.mol
MSDS File:
SDS
Last updated:2024-10-31 13:32:20

Methyl pyruvate Properties

Melting point -22 °C
Boiling point 134-137 °C (lit.)
Density 1.13 g/mL at 25 °C (lit.)
refractive index n20/D 1.404(lit.)
Flash point 103 °F
storage temp. 2-8°C
solubility ethanol: soluble1.1g/10 mL, clear, colorless to almost colorless
form liquid
color Yellow
Water Solubility Soluble in chloroform, methanol, ether, alcohol. Slightly soluble in water.
Merck 14,8021
BRN 1361953
LogP -0.159 (est)
CAS DataBase Reference 600-22-6(CAS DataBase Reference)
FDA UNII 3KJM65G5XL
NIST Chemistry Reference Propanoic acid, 2-oxo-, methyl ester(600-22-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P261
Hazard Codes  Xi,F
Risk Statements  10
Safety Statements  23-24/25-16
RIDADR  UN 3272 3/PG 3
WGK Germany  3
10-21
HazardClass  3
PackingGroup  III
HS Code  29183000
NFPA 704
2
2 0

Methyl pyruvate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 371173 Methyl pyruvate 90%, technical grade 600-22-6 25g $38.9 2024-03-01 Buy
Sigma-Aldrich 371173 Methyl pyruvate 90%, technical grade 600-22-6 100g $45.2 2024-03-01 Buy
TCI Chemical P0580 Methyl Pyruvate >97.0%(GC) 600-22-6 25mL $38 2024-03-01 Buy
TCI Chemical P0580 Methyl Pyruvate >97.0%(GC) 600-22-6 500mL $186 2024-03-01 Buy
Alfa Aesar A13966 Methyl pyruvate, 98% 600-22-6 25g $35.65 2024-03-01 Buy
Product number Packaging Price Buy
371173 25g $38.9 Buy
371173 100g $45.2 Buy
P0580 25mL $38 Buy
P0580 500mL $186 Buy
A13966 25g $35.65 Buy

Methyl pyruvate Chemical Properties,Uses,Production

Chemical Properties

Methyl pyruvate is a clear, light yellow, and flammable liquid.

Uses

Methyl pyruvate may be used to investigate the adsorption and reactivity of methyl pyruvate on Pt{111}. It may be used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

Uses

Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increases free calcium ion concentration in the cytosol of pancreatic cells. It is used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

Preparation

Methyl pyruvate has been prepared from the silver salt of pyruvic acid and methyl iodide; from the free acid, by the ethanol-vapor method without a catalyst, by azeotropic removal of the water produced by the reaction of methanol in the presence of p-toluenesulfonic acid (the present method), and by refluxing with methanol in ethylene dichloride using ethanesulfonic acid as a catalyst (73% yield). Pyruvic esters have also been prepared by the catalytic dehydrogenation of lactic acid esters and by the oxidation of ethyl lactate with potassium permanganate.
DOI: 10.15227/orgsyn.024.0072

Definition

ChEBI: Methyl pyruvate is a pyruvate ester resultinf grom the formal condensation of the carboxy group of pyruvic acid with the hydroxy group of methanol. It is a pyruvate ester and a methyl ester. It derives from a pyruvic acid.

General Description

Methyl pyruvate is a pyruvic ester. Surface conditions during Pt/silica EUROPT-1 modified by cinchonidine catalyzed by enantioselective hydrogenation of methyl pyruvate to R-(+)-methyl lactate were investigated. Enantioselective hydrogenation of methyl pyruvate over finely dispersed polyvinylpyrrolidone-stabilized and the corresponding alumina-supported iridium clusters modified with cinchonidine was studied. The molecular orientation and conformation of methyl pyruvate on Ni(111) surface has been investigated in the temperature range 105-220K. Methyl pyruvate is reported to stimulate insulin secretion in vitro and in vivo.

80-62-6
50-00-0
600-22-6
Synthesis of Methyl pyruvate from Methyl methacrylate
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View Lastest Price from Methyl pyruvate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl pyruvate pictures 2024-11-02 Methyl pyruvate
600-22-6
US $20.00 / kg 1kg 99.9% 10000 Hebei Miaoyin Technology Co.,Ltd
Methyl pyruvate pictures 2024-11-01 Methyl pyruvate
600-22-6
US $56.00 / kg 1kg 99% 5000kg/week Hebei Zhuanglai Chemical Trading Co.,Ltd
Methyl pyruvate pictures 2024-10-31 Methyl pyruvate
600-22-6
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
  • Methyl pyruvate pictures
  • Methyl pyruvate
    600-22-6
  • US $20.00 / kg
  • 99.9%
  • Hebei Miaoyin Technology Co.,Ltd
  • Methyl pyruvate pictures
  • Methyl pyruvate
    600-22-6
  • US $56.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
  • Methyl pyruvate pictures
  • Methyl pyruvate
    600-22-6
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Weibang Biotechnology Co., Ltd
2-oxo-propionicacidmethylester Methylglyoxylic acid methyl ester PYR ME PYRUVIC ACID METHYL ESTER PAME 2-OXOPROPANOIC ACID METHYL ESTER METHYL 2-OXO-PROPIONATE METHYL PYRUVATE 97% METHYL PYRUVATE, TECH., 90% PYRUVIC ACID METHYL ESTER 97+% Methylpyruvate,96% ketopropionic acid methyl ester METHYL PYRUVATE Methyl acetoformate 2-Oxopropanoic acid methyl cis-Pyruvic acid methyl ester trans-Pyruvic acid methyl ester Methyl pyruvate, 94% 25GR Methyl pyruvate,94% Methyl pyruvate 90%, technical grade Methyl Pyruvate , 97.0%(GC) ksby Methyl pyruvate , technical grade MethylPyruvate> Methyl pyruvate CAS:600-22-6 METHYL 2-OXOPROPANOATE Propanoic acid, 2-oxo-, methyl ester Methyl pyruyate 600-22-6 CH3COCO2CH3 CH3COCOOCH3 Esters Organic Building Blocks C2 to C5 Carbonyl Compounds Building Blocks Building Blocks C2 to C5 Carbonyl Compounds Chemical Synthesis Esters Organic Building Blocks PyruvicAcidSeries bc0001 600-22-6