ChemicalBook >> CAS DataBase List >>N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
- CAS No.
- 142808-44-4
- Chemical Name:
- N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
- Synonyms
- Gemcitabine 3'-CE Phosphoramidite;Gemcitabine 3'-CE Phosphoramidite;N4-Bz-DMT-2',2'-difluoro-dC-CE-Phosphoramidite;DMTr-2',2'-diFluoro-dC(Bz)-3'-CE-Phosphoramidite;DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite;DMTr-2’,2’-di fluoro-dC(Bz)-3’-CED-phosphoramidite;5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite;5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite;N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite;N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine
- CBNumber:
- CB84659422
- Molecular Formula:
- C46H50F2N5O8P
- Molecular Weight:
- 869.89
- MDL Number:
- MOL File:
- 142808-44-4.mol
Last updated:2022-08-26 12:23:49
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | PB158887 | N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite | 142808-44-4 | 5mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | PB158887 | N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite | 142808-44-4 | 10mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | PB158887 | N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite | 142808-44-4 | 25mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | PB158887 | N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite | 142808-44-4 | 50mg | $190 | 2021-12-16 | Buy |
| Biosynth Carbosynth | PB158887 | N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite | 142808-44-4 | 100mg | $250 | 2021-12-16 | Buy |
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Chemical Properties,Uses,Production
Uses
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
1.Dissolve 5'-Dimethoxytrityl-N 4-benzoyl-2',2'-difluoro-2'-deoxycytidine (1 equiv., 0.4 mmol, 270 mg)in anhydrous acetonitrile (6 ml).
2.Add 0.5 M solution of ethylothiotetrazole (1.6 equiv., 0.65 mM, 1.3 ml) in anhydrous acetonitrile and 2-cyanoethyl-bis-(N,N'-diisopropropyl)phosphoramidite (1.43 equiv., 0.57 mmol, 0.2 ml) to the above solution.
3.Stir the reaction mixture at room temperature for 1 h to obtain product.
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Preparation Products And Raw materials
Raw materials
Preparation Products
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21669 | 55 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10312 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9980 | 58 |
| Chemtour Biotech Co., Ltd | +8617327281506 | market@chemtour.com | China | 1460 | 58 |
| PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD | 0371-55159968 18137130222 | haifeng.zhang@pannacean.com | China | 461 | 58 |
| Young Lively PharminBlock Co.,Ltd | +undefined18600731423 | jason_gao@yl-pharminblock.com | China | 1944 | 58 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9415 | 66 |
| ATK CHEMICAL COMPANY LIMITED | 3429815786 13301662590 | sales@atkchemical.com | China | 10220 | 55 |
| Wuhu Huaren Science and Technology Co., Ltd. | 0553-0553-5842013-801 18155347026 | jinhuaren@huarensh.com | China | 715 | 58 |
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine
5'-O-DMT-N4-Benzoyl-2',2'-difluoro-2'-deoxycytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2',2'-difluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
N4-Benzoyl-5’-O-(4,4’-dimethoxy trityl) -2’,2’-difluoro-2’-deoxycytidine 3’-O-[(2-cyanoethyl) (N,N-diisopropyl)]-phosphoramidite
DMTr-2’,2’-di fluoro-dC(Bz)-3’-CED-phosphoramidite
N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
N4-Bz-DMT-2',2'-difluoro-dC-CE-Phosphoramidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
(2R,3R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4,4-difluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
Gemcitabine 3'-CE Phosphoramidite
DMTr-2',2'-diFluoro-dC(Bz)-3'-CE-Phosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMTr-2', 2'-difluorocytidine 3'-cyanoethyl phosphoramidite
N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine-3'-cyanoethylPhosphoramidite
DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
Gemcitabine 3'-CE Phosphoramidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
142808-44-4
C46H50F2N5O8P
Other
Phosphoramidite