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Padanamide A

Padanamide A Structure
Padanamide A structure
CAS No.
1314881-80-5
Chemical Name:
Padanamide A
Synonyms
Padanamide A;(S)-N-((2S,3S,4S)-5-(((S)-1-carbamoyl-2-oxopyrrolidin-3-yl)amino)-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl)-2-((2R,3R)-3-hydroxy-2-(2-methoxyacetamido)-4-methylpentanoyl)hexahydropyridazine-3-carboxamide
CBNumber:
CB84666767
Molecular Formula:
C31H47N7O9
Molecular Weight:
661.74638
MDL Number:
MFCD33021590
MOL File:
1314881-80-5.mol
Last updated:2023-05-21 10:59:17
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Padanamide A Properties

Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 13.24±0.46(Predicted)

Padanamide A price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25085 Padanamide A ≥95% 1314881-80-5 1mg $153 2024-03-01 Buy
Cayman Chemical 25085 Padanamide A ≥95% 1314881-80-5 5mg $533 2024-03-01 Buy
AK Scientific 3522DL (3S)-N-[(2S,3S,4S)-5-[[(3S)-1-Carbamoyl-2-oxopyrrolidin-3-yl]amino]-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl]-2-[(2R,3R)-3-hydroxy-2-[(2-methoxyacetyl)amino]-4-methylpentanoyl]diazinane-3-carboxamide 1314881-80-5 1mg $268 2021-12-16 Buy
Product number Packaging Price Buy
25085 1mg $153 Buy
25085 5mg $533 Buy
3522DL 1mg $268 Buy

Padanamide A Chemical Properties,Uses,Production

Description

Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species.1 It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC50 value of approximately 60 μg/ml.2,3

References

1. Nam, S.J., Kauffman, C.A., Jensen, P.R., et al. Isolation and characterization of actinoramides A-C, highly modified peptides from a marine Streptomyces sp Tetrahedron 67(35),6707-6712(2011).
2. Cheng, K.-C., Cao, S., Raveh, A., et al. Actinoramide A identified as a potent antimalarial from titration-based screening of marine natural product extracts J. Nat. Prod. 78(10),2411-2422(2015).
3. Williams, D.E., Dalisay, D.S., Patrick, B.O., et al. Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment Org. Lett. 13(15),3936-3939(2011).

Padanamide A Preparation Products And Raw materials

Raw materials

Preparation Products

Padanamide A Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8860 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
Supplier Advantage
BOC Sciences 		58
Shanghai Hongye Biotechnology Co. Ltd 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Padanamide A (S)-N-((2S,3S,4S)-5-(((S)-1-carbamoyl-2-oxopyrrolidin-3-yl)amino)-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl)-2-((2R,3R)-3-hydroxy-2-(2-methoxyacetamido)-4-methylpentanoyl)hexahydropyridazine-3-carboxamide 1314881-80-5